| Type | Description |
|---|---|
| Definition | PHD finger protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:05:00 | PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks. | 32232336 |
| 2020-01-25 14:06:00 | The HCF-1:ChREBP complex resides at lipogenic gene promoters, where HCF-1 regulates H3K4 trimethylation to prime recruitment of the Jumonji C domain-containing histone demethylase PHF2 for epigenetic activation of these promoters.. these findings define HCF-1's interaction with ChREBP as a previously unappreciated mechanism whereby glucose signals are both relayed to ChREBP and transmitted for epigenetic regulation | 31227231 |
| 2019-12-14 11:30:00 | lower expression of PHF2 promoted hepatocellular carcinoma (HCC) cell migration and linked to worse overall survival in HCC patients. Finally, the negative correlation between miR-221 and PHF2 expression levels in HCC specimens was further confirmed. | 31214616 |
| 2019-09-21 11:43:00 | PHF2 is a negative epigenetic regulator of MK and erythroid differentiation. | 29336484 |
| 2018-07-14 10:07:00 | Our results demonstrate that the promotes PHF2 expression, and suggest that PHF2 (low) expression works with the IKAduanyu1670 gene deletion to drive oncogenesis of ALL | 28994305 |
| Type | IDs |
|---|---|
| Synonymous | CENP-35, GRC5, JHDM1E, KDM7C |
| Gene |
UniProtKB-ID:
PHF2_HUMAN
UniprotKB:
O75151
UniParc:
UPI0000211A97
EMBL:
AB014562,
AL359181,
CH471089,
AL834263,
AF043725,
AL353629
Ensembl:
ENSG00000197724
KO:
hsa:5253
|
| Nucleutide sequences |
EMBL-CDS:
BAA31637.2,
AAD21791.1,
CAD38938.1,
EAW62867.1
Ensembl_TRS:
ENST00000359246
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000352185
RefSeq:
NP_005383.3,
XP_005252108.1,
XP_006717206.1
|
| Others |
UniRef100:
UniRef100_O75151
UniRef90:
UniRef90_O75151
UniRef50:
UniRef50_O75151
UniGene:
Hs.211441
CCDS:
CCDS35069.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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