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5244 ABCB4

5244

ABCB4

ATP binding cassette subfamily B member 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition ATP binding cassette subfamily B member 4

研究结论

Date Results Publications
2021-02-13 13:20:00 ABCB4 disease: Many faces of one gene deficiency. 31759867
2020-09-19 16:27:00 ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans. 32058310
2020-08-29 12:44:00 Elevated hepatic MDR3/ABCB4 is directly mediated by MiR-378a-5p in human obstructive cholestasis. 30964181
2020-07-11 11:29:00 Our results demonstrated increased expression of ABCB11 and ABCB4 on protein as well as RNA level in primary sclerosing cholangitis, and the expression pattern correlated with disease progression. 31886153
2020-05-02 10:49:00 This study determined the cryo-EM structure of nanodisc-reconstituted human ABCB4 trapped in an ATP-bound state at a resolution of 3.2 A 31873305

名称对应

Type IDs
Synonymous ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3
Gene
UniProtKB-ID: MDR3_HUMAN
UniprotKB: P21439
UniParc: UPI000013D66B, UPI000004C4B9, UPI000012EE8B
EMBL: Z35284, AC005045, AC006154, AC005068, M23234, EF034088, CH471091, CH236949, X06181
Ensembl: ENSG00000005471
KO: hsa:5244
Nucleutide sequences
EMBL-CDS: EAW76951.1, CAA84542.1, EAW76950.1, EAW76948.1, EAW76952.1, EAW76946.1, AAA36207.1, EAL24175.1, ABJ53424.1, EAL24176.1, EAW76947.1, CAA29547.1, EAL24174.1
Ensembl_TRS: ENST00000265723, ENST00000453593, ENST00000358400, ENST00000359206, ENST00000649586
Protein sequencees
Ensembl_PRO: ENSP00000496956, ENSP00000351172, ENSP00000392983, ENSP00000265723, ENSP00000352135
RefSeq: XP_011514612.3, XP_011514614.3, XP_011514615.2, XP_016867812.1, XP_011514611.3, NP_000434.1, XP_011514610.3, XP_011514617.2, NP_061338.1, NP_061337.1, XP_011514613.3
Others
UniRef100: UniRef100_P21439
UniRef90: UniRef90_P21439
UniRef50: UniRef50_P21439
UniGene: Hs.654403
CCDS: CCDS5605.1, CCDS5606.1, CCDS5607.1

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