| Type | Description |
|---|---|
| Definition | ATPase H+ transporting V1 subunit A |
| Date | Results | Publications |
|---|---|---|
| 2019-07-13 10:59:00 | This study provides evidence that de novo heterozygous ATP6V1A mutations cause a developmental encephalopathy with a pathomechanism that involves perturbations of lysosomal homeostasis and neuronal connectivity. | 29668857 |
| 2019-01-12 10:06:00 | In conclusion, YY1 may play an important regulatory role in ATP6V1A expression with potential mechanistic and clinical implications in gastric cancer. | 28592880 |
| 2017-05-06 11:31:00 | We report biallelic mutations in ATP6V1E1 and ATP6V1A, respectively encoding the E1 and A subunits of the V1 domain of V-ATPase, as a cause of distinct metabolic and multisystemic cutis laxa entities. | 28065471 |
| 2016-03-12 10:36:00 | V1A subunit of V-ATPase has a role in the progression and prognosis of gastric cancer. | 25652905 |
| 2012-10-27 10:14:00 | Data show that the signaling pathway initiates acidosis-induced V-ATPase trafficking in salivary ducts via regulation of Rab11b expression. | 22561749 |
| Type | IDs |
|---|---|
| Synonymous | ARCL2D, ATP6A1, ATP6V1A1, HO68, IECEE3, VA68, VPP2, Vma1 |
| Gene |
UniProtKB-ID:
VATA_HUMAN
UniprotKB:
P38606
UniParc:
UPI0000209F8E,
UPI000013809A
EMBL:
AC079944,
AK293804,
AF113129,
L09235,
BT006672,
AK314779,
CH471052,
BC013138,
AC108693
Ensembl:
ENSG00000114573
KO:
hsa:523
|
| Nucleutide sequences |
EMBL-CDS:
BAG37315.1,
AAF14870.1,
AAP35318.1,
AAH13138.1,
EAW79625.1,
BAH11601.1,
AAA83249.1,
EAW79626.1
Ensembl_TRS:
ENST00000273398
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000273398
RefSeq:
NP_001681.2
|
| Others |
UniRef100:
UniRef100_P38606
UniRef90:
UniRef90_P38606
UniRef50:
UniRef50_P38606
UniGene:
Hs.477155
CCDS:
CCDS2976.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33060197 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science David E Gordon , Joseph Hiatt , Mehdi Bouhaddou , Veronica V Rezelj , Svenja Ulferts , Hannes Braberg , Alexander S Jureka , Kirsten Obernier , Jeffrey Z Guo , Jyoti Batra , Robyn M Kaake , Andrew R Weckstein , Tristan W Owens , Meghna Gupta , Sergei Pourmal , Erron W Titus , Merve Cakir , Margaret Soucheray , Michael McGregor , Zeynep Cakir , Gwendolyn Jang , Matthew J O'Meara , Tia A Tummino , Ziyang Zhang , Helene Foussard , Ajda Rojc , Yuan Zhou , Dmitry Kuchenov , Ruth Hüttenhain , Jiewei Xu , Manon Eckhardt , Danielle L Swaney , Jacqueline M Fabius , Manisha Ummadi , Beril Tutuncuoglu , Ujjwal Rathore , Maya Modak , Paige Haas , Kelsey M Haas , Zun Zar Chi Naing , Ernst H Pulido , Ying Shi , Inigo Barrio-Hernandez , Danish Memon , Eirini Petsalaki , Alistair Dunham , Miguel Correa Marrero , David Burke , Cassandra Koh , Thomas Vallet , Jesus A Silvas , Caleigh M Azumaya , Christian Billesbølle , Axel F Brilot , Melody G Campbell , Amy Diallo , Miles Sasha Dickinson , Devan Diwanji , Nadia Herrera , Nick Hoppe , Huong T Kratochvil , Yanxin Liu , Gregory E Merz , Michelle Moritz , Henry C Nguyen , Carlos Nowotny , Cristina Puchades , Alexandrea N Rizo , Ursula Schulze-Gahmen , Amber M Smith , Ming Sun , Iris D Young , Jianhua Zhao , Daniel Asarnow , Justin Biel , Alisa Bowen , Julian R Braxton , Jen Chen , Cynthia M Chio , Un Seng Chio , Ishan Deshpande , Loan Doan , Bryan Faust , Sebastian Flores , Mingliang Jin , Kate Kim , Victor L Lam , Fei Li , Junrui Li , Yen-Li Li , Yang Li , Xi Liu , Megan Lo , Kyle E Lopez , Arthur A Melo , Frank R Moss , Phuong Nguyen , Joana Paulino , Komal Ishwar Pawar , Jessica K Peters , Thomas H Pospiech , Maliheh Safari , Smriti Sangwan , Kaitlin Schaefer , Paul V Thomas , Aye C Thwin , Raphael Trenker , Eric Tse , Tsz Kin Martin Tsui , Feng Wang , Natalie Whitis , Zanlin Yu , Kaihua Zhang , Yang Zhang , Fengbo Zhou , Daniel Saltzberg , QCRG Structural Biology Consortium , Anthony J Hodder , Amber S Shun-Shion , Daniel M Williams , Kris M White , Romel Rosales , Thomas Kehrer , Lisa Miorin , Elena Moreno , Arvind H Patel , Suzannah Rihn , Mir M Khalid , Albert Vallejo-Gracia , Parinaz Fozouni , Camille R Simoneau , Theodore L Roth , David Wu , Mohd Anisul Karim , Maya Ghoussaini , Ian Dunham , Francesco Berardi , Sebastian Weigang , Maxime Chazal , Jisoo Park , James Logue , Marisa McGrath , Stuart Weston , Robert Haupt , C James Hastie , Matthew Elliott , Fiona Brown , Kerry A Burness , Elaine Reid , Mark Dorward , Clare Johnson , Stuart G Wilkinson , Anna Geyer , Daniel M Giesel , Carla Baillie , Samantha Raggett , Hannah Leech , Rachel Toth , Nicola Goodman , Kathleen C Keough , Abigail L Lind , Zoonomia Consortium , Reyna J Klesh , Kafi R Hemphill , Jared Carlson-Stevermer , Jennifer Oki , Kevin Holden , Travis Maures , Katherine S Pollard , Andrej Sali , David A Agard , Yifan Cheng , James S Fraser , Adam Frost , Natalia Jura , Tanja Kortemme , Aashish Manglik , Daniel R Southworth , Robert M Stroud , Dario R Alessi , Paul Davies , Matthew B Frieman , Trey Ideker , Carmen Abate , Nolwenn Jouvenet , Georg Kochs , Brian Shoichet , Melanie Ott , Massimo Palmarini , Kevan M Shokat , Adolfo GarcÃa-Sastre , Jeremy A Rassen , Robert Grosse , Oren S Rosenberg , Kliment A Verba , Christopher F Basler , Marco Vignuzzi , Andrew A Peden , Pedro Beltrao , Nevan J Krogan |
2020-12-04 | - |
| 33144569 |
A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export. Nat Commun Dick J H van den Boomen , Agata Sienkiewicz , Ilana Berlin , Marlieke L M Jongsma , Daphne M van Elsland , J Paul Luzio , Jacques J C Neefjes , Paul J Lehner |
2020-11-03 | - |
| 32780723 |
JCI Insight Wenjun Lan , Patricia Santofimia-Castaño , Mirna Swayden , Yi Xia , Zhengwei Zhou , Stephane Audebert , Luc Camoin , Can Huang , Ling Peng , Ana Jiménez-Alesanco , Adrián Velázquez-Campoy , Olga Abián , Gwen Lomberk , Raul Urrutia , Bruno Rizzuti , Vincent Geli , Philippe Soubeyran , José L Neira , Juan Iovanna |
2020-09-17 | - |
| 32353859 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature David E Gordon , Gwendolyn M Jang , Mehdi Bouhaddou , Jiewei Xu , Kirsten Obernier , Kris M White , Matthew J O'Meara , Veronica V Rezelj , Jeffrey Z Guo , Danielle L Swaney , Tia A Tummino , Ruth Hüttenhain , Robyn M Kaake , Alicia L Richards , Beril Tutuncuoglu , Helene Foussard , Jyoti Batra , Kelsey Haas , Maya Modak , Minkyu Kim , Paige Haas , Benjamin J Polacco , Hannes Braberg , Jacqueline M Fabius , Manon Eckhardt , Margaret Soucheray , Melanie J Bennett , Merve Cakir , Michael J McGregor , Qiongyu Li , Bjoern Meyer , Ferdinand Roesch , Thomas Vallet , Alice Mac Kain , Lisa Miorin , Elena Moreno , Zun Zar Chi Naing , Yuan Zhou , Shiming Peng , Ying Shi , Ziyang Zhang , Wenqi Shen , Ilsa T Kirby , James E Melnyk , John S Chorba , Kevin Lou , Shizhong A Dai , Inigo Barrio-Hernandez , Danish Memon , Claudia Hernandez-Armenta , Jiankun Lyu , Christopher J P Mathy , Tina Perica , Kala Bharath Pilla , Sai J Ganesan , Daniel J Saltzberg , Ramachandran Rakesh , Xi Liu , Sara B Rosenthal , Lorenzo Calviello , Srivats Venkataramanan , Jose Liboy-Lugo , Yizhu Lin , Xi-Ping Huang , YongFeng Liu , Stephanie A Wankowicz , Markus Bohn , Maliheh Safari , Fatima S Ugur , Cassandra Koh , Nastaran Sadat Savar , Quang Dinh Tran , Djoshkun Shengjuler , Sabrina J Fletcher , Michael C O'Neal , Yiming Cai , Jason C J Chang , David J Broadhurst , Saker Klippsten , Phillip P Sharp , Nicole A Wenzell , Duygu Kuzuoglu-Ozturk , Hao-Yuan Wang , Raphael Trenker , Janet M Young , Devin A Cavero , Joseph Hiatt , Theodore L Roth , Ujjwal Rathore , Advait Subramanian , Julia Noack , Mathieu Hubert , Robert M Stroud , Alan D Frankel , Oren S Rosenberg , Kliment A Verba , David A Agard , Melanie Ott , Michael Emerman , Natalia Jura , Mark von Zastrow , Eric Verdin , Alan Ashworth , Olivier Schwartz , Christophe d'Enfert , Shaeri Mukherjee , Matt Jacobson , Harmit S Malik , Danica G Fujimori , Trey Ideker , Charles S Craik , Stephen N Floor , James S Fraser , John D Gross , Andrej Sali , Bryan L Roth , Davide Ruggero , Jack Taunton , Tanja Kortemme , Pedro Beltrao , Marco Vignuzzi , Adolfo GarcÃa-Sastre , Kevan M Shokat , Brian K Shoichet , Nevan J Krogan |
2020-07-01 | - |
| 32416067 |
Mol Cell Shaokun Shu , Hua-Jun Wu , Jennifer Y Ge , Rhamy Zeid , Isaac S Harris , Bojana JovanoviÄ , Katherine Murphy , Binbin Wang , Xintao Qiu , Jennifer E Endress , Jaime Reyes , Klothilda Lim , Alba Font-Tello , Sudeepa Syamala , Tengfei Xiao , Chandra Sekhar Reddy Chilamakuri , Evangelia K Papachristou , Clive D'Santos , Jayati Anand , Kunihiko Hinohara , Wei Li , Thomas O McDonald , Adrienne Luoma , Rebecca J Modiste , Quang-De Nguyen , Brittany Michel , Paloma Cejas , Cigall Kadoch , Jacob D Jaffe , Kai W Wucherpfennig , Jun Qi , X Shirley Liu , Henry Long , Myles Brown , Jason S Carroll , Joan S Brugge , James Bradner , Franziska Michor , Kornelia Polyak |
2020-06-18 | - |
| 31995728 |
Mol Cell Jingyue Jia , Bhawana Bissa , Lukas Brecht , Lee Allers , Seong Won Choi , Yuexi Gu , Mark Zbinden , Mark R Burge , Graham Timmins , Kenneth Hallows , Christian Behrends , Vojo Deretic |
2020-03-05 | - |
| 31980649 |
Nat Commun Susan A Kennedy , Mohamed-Ali Jarboui , Sriganesh Srihari , Cinzia Raso , Kenneth Bryan , Layal Dernayka , Theodosia Charitou , Manuel Bernal-Llinares , Carlos Herrera-Montavez , Aleksandar Krstic , David Matallanas , Max Kotlyar , Igor Jurisica , Jasna Curak , Victoria Wong , Igor Stagljar , Thierry LeBihan , Lisa Imrie , Priyanka Pillai , Miriam A Lynn , Erik Fasterius , Cristina Al-Khalili Szigyarto , James Breen , Christina Kiel , Luis Serrano , Nora Rauch , Oleksii Rukhlenko , Boris N Kholodenko , Luis F Iglesias-Martinez , Colm J Ryan , Ruth Pilkington , Patrizia Cammareri , Owen Sansom , Steven Shave , Manfred Auer , Nicola Horn , Franziska Klose , Marius Ueffing , Karsten Boldt , David J Lynn , Walter Kolch |
2020-01-24 | - |
| 31478661 |
J. Proteome Res. Luiz E Silva , Renan C Souza , Eduardo S Kitano , Lucas F Monteiro , Leo K Iwai , Fabio L Forti |
2019-10-04 | - |
| 31536960 |
iScience Mohamed Taha Moutaoufik , Ramy Malty , Shahreen Amin , Qingzhou Zhang , Sadhna Phanse , Alla Gagarinova , Mara Zilocchi , Larissa Hoell , Zoran Minic , Maria Gagarinova , Hiroyuki Aoki , Jocelyn Stockwell , Matthew Jessulat , Florian Goebels , Kirsten Broderick , Nichollas E Scott , James Vlasblom , Gabriel Musso , Bhanu Prasad , Eleonora Lamantea , Barbara Garavaglia , Alex Rajput , Kei Murayama , Yasushi Okazaki , Leonard J Foster , Gary D Bader , Francisco S Cayabyab , Mohan Babu |
2019-09-27 | - |
| 31300519 |
PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation. J. Neurosci. Cristina Guardia-Laguarta , Yuhui Liu , Knut H Lauritzen , Hediye Erdjument-Bromage , Brittany Martin , Theresa C Swayne , Xuejun Jiang , Serge Przedborski |
2019-09-04 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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