| Type | Description |
|---|---|
| Definition | profilin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:29:00 | Profilin-1 is dysregulated in endometroid (type I) endometrial cancer promoting cell proliferation and inhibiting pro-inflammatory cytokine production. | 32800551 |
| 2021-03-13 13:17:00 | Actin-binding protein profilin1 promotes aggressiveness of clear-cell renal cell carcinoma cells. | 32883810 |
| 2021-02-20 13:31:00 | A Familial Phenotypic and Genetic Study of Mutations in PFN1 Associated with Amyotrophic Lateral Sclerosis. | 31802421 |
| 2021-02-13 13:21:00 | Mutation of PFN1 Gene in an Early Onset, Polyostotic Paget-like Disease. | 32392277 |
| 2020-08-22 15:31:00 | Profilin-Mediated Actin Allocation Regulates the Growth of Epithelial Microvilli. | 31607529 |
| Type | IDs |
|---|---|
| Synonymous | ALS18 |
| Gene |
UniProtKB-ID:
PROF1_HUMAN
UniprotKB:
P07737
UniParc:
UPI000013C879
EMBL:
GU727630,
BC006768,
J03191,
BT007001,
CR407670,
CH471108,
BC002475,
BC015164,
BC057828,
BC013439,
AK312168
Ensembl:
ENSG00000108518
KO:
hsa:5216
|
| Nucleutide sequences |
EMBL-CDS:
EAW90381.1,
AAH02475.1,
EAW90384.1,
CAG28598.1,
AAH13439.1,
AAA36486.1,
ADU87632.1,
AAH57828.1,
BAG35102.1,
AAP35647.1,
AAH15164.1,
EAW90383.1,
AAH06768.1
Ensembl_TRS:
ENST00000225655
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000225655
RefSeq:
NP_005013.1,
NP_001362920.1
|
| Others |
UniRef100:
UniRef100_P07737
UniRef90:
UniRef90_P07737
UniRef50:
UniRef50_P07737
UniGene:
Hs.494691
CCDS:
CCDS11061.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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