| Type | Description |
|---|---|
| Definition | potassium inwardly-rectifying channel, subfamily K, member 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 11:00:00 | Twik-2-/- mice have enhanced vasocontractility in the distal pulmonary vasculature. | 30632293 |
| 2019-03-09 10:07:00 | Deletion of Kcnk6 (encoding two-pore domain K(+) channel TWIK2) prevents NLR Family, Pyrin Domain-Containing 3 Protein (NLRP3) inflammasome activation in macrophages and suppressed sepsis-induced lung inflammation. Adoptive transfer of Kcnk6(-/-) macrophages into mouse airways after macrophage depletion also prevents inflammatory lung injury. | 29958799 |
| 2015-01-24 11:31:00 | mice deficient in the TWIK-2 channel develop pulmonary hypertension between 8 and 20 weeks of age through a mechanism involving Rho-kinase. | 25245387 |
| Type | IDs |
|---|---|
| Synonymous | D7Ertd764e, Toss, Twik2 |
| Gene |
UniProtKB-ID:
Q3TQ68_MOUSE,
Q3TBV4_MOUSE,
Q3V1G1_MOUSE
UniprotKB:
Q3TQ68,
Q3TBV4,
Q3V1G1
UniParc:
UPI00001E4041,
UPI00005B1FDF,
UPI00005AB88A
EMBL:
AC164564,
AK163847,
AK171038,
DQ185135,
AK132480
Ensembl:
ENSMUSG00000046410
KO:
mmu:52150
|
| Nucleutide sequences |
EMBL-CDS:
BAE37517.1,
BAE42203.1,
ABA28316.1,
BAE21190.1
Ensembl_TRS:
ENSMUST00000085818
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000082975
RefSeq:
NP_001028697.2
|
| Others |
UniRef100:
UniRef100_Q3TBV4,
UniRef100_Q3V1G1
UniRef90:
UniRef90_Q3TBV4
UniRef50:
UniRef50_Q3TBV4
UniGene:
Mm.24877
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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