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5214 PFKP

5214

PFKP

phosphofructokinase, platelet

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosphofructokinase, platelet

研究结论

Date Results Publications
2021-03-13 13:21:00 Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches. 33141153
2021-03-13 13:18:00 Prognostic and therapeutic relevance of phosphofructokinase platelet-type (PFKP) in breast cancer. 32919954
2020-07-25 10:58:00 The observed changes are suggestive of compositional changes in the subunit makeup of HK and PFK. The implication of these findings in relation to energy status of the diabetic erythrocyte and its interrelationship with loss of cell deformability are discussed here. 31520487
2019-09-21 11:59:00 PFKP expression was significantly increased in OSCC patients. 29894707
2019-02-09 10:30:00 EGFR-phosphorylated platelet isoform of phosphofructokinase 1 promotes PI3K activation, promoting the Warburg effect, tumor cell proliferation, and brain tumorigenesis. 29677490

名称对应

Type IDs
Synonymous ATP-PFK, PFK-C, PFK-P, PFKF
Gene
UniProtKB-ID: PFKAP_HUMAN, B1APP6_HUMAN
UniprotKB: Q01813, B1APP6
UniParc: UPI00000012D2, UPI0000141823, UPI0007AA7DEA
EMBL: BC002536, BC029138, AL451164, AL731533, AK092597, AK291841, KF455188, D25328, M64784
Ensembl: ENSG00000067057
KO: hsa:5214
Nucleutide sequences
EMBL-CDS: AAA36435.1, BAF84530.1, AAH29138.1, BAG52577.1, BAA04998.1, AAH02536.1
Ensembl_TRS: ENST00000381125, ENST00000381075, ENST00000415005
Protein sequencees
Ensembl_PRO: ENSP00000370517, ENSP00000370465, ENSP00000408858
RefSeq: XP_024303806.1, NP_001309997.1, XP_005252522.1, NP_001309996.1, NP_001309998.1, NP_002618.1, NP_001310001.1, XP_006717512.1, NP_001310003.1, NP_001309999.1, NP_001229268.1, NP_001332873.1, NP_001310000.1, XP_005252523.1, NP_001310002.1
Others
UniRef100: UniRef100_Q01813
UniRef90: UniRef90_Q01813
UniRef50: UniRef50_Q01813
UniGene: Hs.26010
CCDS: CCDS55698.1, CCDS7059.1

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