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5213 PFKM

5213

PFKM

phosphofructokinase, muscle

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosphofructokinase, muscle

研究结论

Date Results Publications
2021-03-13 13:21:00 Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches. 33141153
2021-02-27 13:45:00 Phosphofructokinase-M inhibits cell growth via modulating the FOXO3 pathway in renal cell carcinoma cells. 32828317
2020-03-28 12:01:00 The authors experimentally provide evidence for pulsatile PFK-1 activity-induced synchronized dissociation of PKM2 tetramers and the subsequent accumulation of PKM2 dimers under high levels of fructose-1,6-bisphosphate in HeLa cells. 31469100
2019-04-20 10:47:00 MiR-135 targets phosphofructokinase-1 in the ancreatic ductal adenocarcinoma cells. 30778058
2018-08-04 11:13:00 KLK6 may be the key protease involved in the proteolytic modification of PFK-M. 29563071

名称对应

Type IDs
Synonymous ATP-PFK, GSD7, PFK-1, PFK-A, PFK1, PFKA, PFKX, PPP1R122
Gene
UniProtKB-ID: PFKAM_HUMAN, A0A2R8Y891_HUMAN, A0A024R0Y5_HUMAN
UniprotKB: P08237, A0A2R8Y891, A0A024R0Y5
UniParc: UPI0000D621DC, UPI0000000CCC, UPI000014133C, UPI000387BDBF
EMBL: KU178251, M59738, M59737, M59730, CH471111, M59733, M59732, Y00698, AC004801, BC013298, M59739, M59724, BC000534, M59736, AC074029, M59726, M59740, M59729, M59735, M59721, M24925, M59741, J05533, BC012799, M59720, M59728, M59731, M26066, M59734, AK126229, M59722, M59723, M59725, BC021203, M59727
Ensembl: ENSG00000152556
KO: hsa:5213
Nucleutide sequences
EMBL-CDS: AAH21203.1, AAH12799.1, BAC86498.1, AAA82938.1, CAA68692.1, AAH00534.1, AAA36436.1, AAH13298.1, AAA60068.1, AAA79220.1, EAW57975.1, EAW57974.1, ALQ33709.1
Gene_ORFName: hCG_27714
Ensembl_TRS: ENST00000312352, ENST00000359794, ENST00000551804, ENST00000551339, ENST00000547587, ENST00000550345, ENST00000550924, ENST00000340802, ENST00000642730
Protein sequencees
Ensembl_PRO: ENSP00000448253, ENSP00000448177, ENSP00000345771, ENSP00000450369, ENSP00000446945, ENSP00000309438, ENSP00000449426, ENSP00000352842, ENSP00000496597
RefSeq: XP_024304790.1, XP_005269033.1, XP_011536789.1, NP_001341677.1, NP_001160159.1, NP_001341665.1, NP_001341669.1, NP_001341667.1, XP_005269036.1, NP_001341675.1, NP_001341674.1, NP_001341670.1, NP_001341673.1, NP_001341668.1, NP_000280.1, XP_005269031.1, XP_024304788.1, NP_001160160.1, NP_001341671.1, NP_001160158.1, NP_001341672.1, NP_001350548.1, NP_001341676.1, XP_016874958.1, NP_001341664.1, XP_024304789.1, NP_001341666.1
Others
UniRef100: UniRef100_P08237
UniRef90: UniRef90_P08237
UniRef50: UniRef50_P08237
UniGene: Hs.75160
CCDS: CCDS86295.1, CCDS8760.1, CCDS53786.1

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研究热度

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