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52118 Pvr

52118

Pvr

poliovirus receptor

protein-coding

Mus musculus

基因描述

Type Description
Definition poliovirus receptor

研究结论

Date Results Publications
2019-10-19 11:47:00 Results indicate that TIGIT enhanced on tolerant T cells may function as a ligand of its paired receptor CD155 to transduce signaling into its expressing naive T cells to accelerate new TIGIT expressions as well as IL-2 suppression via B lymphocyte-induced maturation protein 1 enhancement. 31022697
2019-09-14 10:10:00 CD155-deleted tumor cells also displayed slower tumor growth and reduced metastases, demonstrating the importance of a tumor-intrinsic role of CD155. CD155 absence on host and tumor cells exerted an even greater inhibition of tumor growth and metastasis. 29757192
2019-03-16 12:11:00 The hybrid complex structure of CD226-ecto binding to the first domain of CD155 (hCD155-D1) reveals a conserved binding interface with the first domain of CD226 (D1), whereas the second domain of CD226 (D2) both provides structural supports for the unique architecture of CD226 and forms direct interactions with CD155. 30591568
2016-09-24 11:26:00 Data show that CD155 protein/CD226 antigen mainly mediates the interaction between NK cells and leukemic cells in acute myeloid leukemia. To investigate the interaction between leukemic cells 26588911
2016-09-03 10:47:00 absence of either CD155 or CD226 in BALB/c mice causes a profound shift in the Natural Killer T-Cells subtype composition in thymus, expanding the frequency and numbers of iNKT1 cells at the expense of iNKT2 cells, as well as iNKT17 cells. 26689152

名称对应

Type IDs
Synonymous 3830421F03Rik, CD155, D7Ertd458e, HVED, PVS, Taa1, Tage4, mE4, necl-5
Gene
UniProtKB-ID: Q8K094_MOUSE
UniprotKB: Q8K094
UniParc: UPI0000025985
EMBL: AK080753, AK038747, AK165873, BC138220, AJ563420, AC149085, BC138219, BC032283
Ensembl: ENSMUSG00000040511
KO: mmu:52118
Nucleutide sequences
EMBL-CDS: BAC38008.1, BAC30124.1, AAI38221.1, AAI38220.1, BAE38429.1, AAH32283.1, CAD91411.1
Ensembl_TRS: ENSMUST00000043517
Protein sequencees
Ensembl_PRO: ENSMUSP00000039205
RefSeq: NP_081790.1
Others
UniRef100: UniRef100_Q8K094
UniRef90: UniRef90_Q8K094
UniRef50: UniRef50_Q8K094
UniGene: Mm.227506

全选

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研究热度

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