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5211 PFKL

5211

PFKL

phosphofructokinase, liver type

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosphofructokinase, liver type

研究结论

Date Results Publications
2021-03-13 13:21:00 Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches. 33141153
2021-02-20 13:28:00 A20 targets PFKL and glycolysis to inhibit the progression of hepatocellular carcinoma. 32015333
2020-02-29 11:06:00 (125)I irradiation upregulated the suppression of miR-338 on PFKL to downregulate the Warburg effect. 31514072
2019-05-04 12:42:00 TAp73 deficiency results in a pronounced reduction in tumorigenic potential, which can be rescued by forced PFKL expression. 30409970
2017-09-30 10:24:00 Liver PFK1 isoform assembles into filaments in a tetramer- and substrate-dependent manner,organizing isoform specific glucose metabolism in cells. 28646105

名称对应

Type IDs
Synonymous ATP-PFK, PFK-B, PFK-L
Gene
UniProtKB-ID: PFKAL_HUMAN, Q7L2M7_HUMAN
UniprotKB: P17858, Q7L2M7
UniParc: UPI000006DD65, UPI0000374D82, UPI0000169D5F
EMBL: X16924, X16923, X16915, X16916, X16922, BC007536, X16930, BC009919, X16911, X16919, X16927, X16929, X16920, X16912, BC008964, X16926, X16921, X15573, BC006422, AP001754, X16913, X16925, BC018295, X16928, X16914, X16918, X16917
Ensembl: ENSG00000141959
KO: hsa:5211
Nucleutide sequences
EMBL-CDS: AAH09919.1, AAH06422.1, AAH07536.1, AAH08964.1, BAA95561.1, CAA33597.1, CAB46744.1, AAH18295.2
Ensembl_TRS: ENST00000349048
Protein sequencees
Ensembl_PRO: ENSP00000269848
RefSeq: XP_011527905.1, XP_024307853.1, XP_016883858.1, NP_001002021.2, NP_002617.3, XP_016883857.1, XP_005261194.1, XP_016883859.1, XP_006724074.1, XP_016883861.1, XP_005261192.1
Others
UniRef100: UniRef100_Q6MZK4, UniRef100_P17858
UniRef90: UniRef90_P17858
UniRef50: UniRef50_P17858
UniGene: Hs.255093
CCDS: CCDS33582.1

全选

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