| Type | Description |
|---|---|
| Definition | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:08:00 | c-Src Promotes Tumorigenesis and Tumor Progression by Activating PFKFB3. | 32209481 |
| 2021-04-03 13:30:00 | CPEB4 Increases Expression of PFKFB3 to Induce Glycolysis and Activate Mouse and Human Hepatic Stellate Cells, Promoting Liver Fibrosis. | 32169429 |
| 2020-11-28 13:10:00 | Activation of the HIF1alpha/PFKFB3 stress response pathway in beta cells in type 1 diabetes. | 31720731 |
| 2020-10-24 14:04:00 | PI3K-Akt-mTOR/PFKFB3 pathway mediated lung fibroblast aerobic glycolysis and collagen synthesis in lipopolysaccharide-induced pulmonary fibrosis. | 32051533 |
| 2020-10-03 12:51:00 | Drive Proliferation in Acute Myeloid Leukemia via the Glycolytic Regulator PFKFB3. | 31862780 |
| Type | IDs |
|---|---|
| Synonymous | IPFK2, PFK2, iPFK-2 |
| Gene |
UniProtKB-ID:
F263_HUMAN,
B7Z8A0_HUMAN
UniprotKB:
Q16875,
B7Z8A0
UniParc:
UPI0001915356,
UPI000002A946,
UPI0000001082,
UPI0001915224,
UPI00001F8ACF
EMBL:
AF041830,
BC040482,
AF041826,
AK291263,
AL359960,
CH471072,
AK303039,
AF041825,
L77662,
AF056320,
AK304450,
AF041831,
AL157395,
AF041828,
AF041823,
AF041829,
D49817,
AF041827,
AF041824,
AF109735
Ensembl:
ENSG00000170525
KO:
hsa:5209
|
| Nucleutide sequences |
EMBL-CDS:
BAF83952.1,
BAA08624.1,
AAC62000.1,
BAH14191.1,
AAL40083.1,
EAW86399.1,
AAH40482.1,
EAW86398.1,
AAB99795.1,
AAD08818.1,
BAH13886.1
Ensembl_TRS:
ENST00000360521,
ENST00000536985,
ENST00000379789,
ENST00000379775
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000369100,
ENSP00000443319,
ENSP00000353712,
ENSP00000369115
RefSeq:
NP_001309945.1,
NP_001138915.1,
XP_016871815.1,
NP_004557.1,
XP_005252521.1,
XP_016871818.1,
NP_001309946.1,
XP_016871817.1,
XP_024303805.1,
XP_011517795.1,
NP_001350474.1,
XP_016871816.1,
NP_001300992.1,
NP_001269559.1
|
| Others |
UniRef100:
UniRef100_Q16875,
UniRef100_B7Z8A0
UniRef90:
UniRef90_Q16875,
UniRef90_Q5R9C1-3
UniRef50:
UniRef50_O60825,
UniRef50_Q16875
UniGene:
Hs.195471
CCDS:
CCDS81439.1,
CCDS7078.1,
CCDS60479.1,
CCDS44353.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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