| Type | Description |
|---|---|
| Definition | ATPase phospholipid transporting 8B1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-29 12:15:00 | Progressive familial intrahepatic cholestasis 1 involves ATP8B1 gene encoding for aminophospholipid flippase FIC1. [review] | 31105019 |
| 2019-06-15 11:12:00 | Mutations in the genes responsible for PFIC may be involved in both young and adults with cryptogenic cholestasis in a considerable number of cases, including in heterozygous status. | 29238877 |
| 2018-08-18 11:44:00 | FIC1, BSEP, and MDR3 represent hepatobiliary transport proteins essential for bile formation. | 28733223 |
| 2018-08-18 10:03:00 | ATP8B1 deficiency caused incomplete polarization of human peripheral blood monocyte-derived macrophages into M2c, a subset alternatively activated macrophages. | 29104077 |
| 2017-09-02 10:49:00 | the first characterisation at the protein level of six ABCB4 variants (D243A, K435T, G535D, I490T, R545C, and S978P) previously found in patients with inflammatory liver diseases or liver cancer, is reported. | 28220208 |
| Type | IDs |
|---|---|
| Synonymous | ATPIC, BRIC, FIC1, ICP1, PFIC, PFIC1 |
| Gene |
UniProtKB-ID:
AT8B1_HUMAN
UniprotKB:
O43520
UniParc:
UPI000013DD54
EMBL:
BC003534,
AC027097,
AF038007,
AF032442
Ensembl:
ENSG00000081923
KO:
hsa:5205
|
| Nucleutide sequences |
EMBL-CDS:
AAC04328.1,
AAH03534.1,
AAC63461.1
Ensembl_TRS:
ENST00000648908
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000497896
RefSeq:
NP_001361315.1,
NP_005594.2,
NP_001361314.1,
XP_011524325.1
|
| Others |
UniRef100:
UniRef100_O43520
UniRef90:
UniRef90_O43520
UniRef50:
UniRef50_O43520
UniGene:
Hs.216623
CCDS:
CCDS11965.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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