| Type | Description |
|---|---|
| Definition | protein phosphatase 1, regulatory subunit 10 |
| Date | Results | Publications |
|---|---|---|
| 2010-11-27 10:34:00 | stimulation of PP1 activity via siRNA mediated knockdown of its interacting protein PNUTS (Phosphatase Nuclear Targeting Subunit) leads to Rb dephosphorylation and apoptosis in cancer cells | 20372802 |
| 2010-01-21 00:00:00 | Protein phosphatase 1 (PP1) and GABA(C) receptors simultaneously bind to different domains of PNUTS, demonstrating that PNUTS crosslinks PP1 and GABA(C) receptors. | 18325784 |
| Type | IDs |
|---|---|
| Synonymous | 2610025H06Rik, Cat53, D17Ertd808e, Fb19, Pnuts |
| Gene |
UniProtKB-ID:
PP1RA_MOUSE
UniprotKB:
Q80W00
UniParc:
UPI000019A3E0,
UPI00004E1951
EMBL:
AJ504718,
BC052059,
BC029765,
AK053183,
CR974451
Ensembl:
ENSMUSG00000039220
KO:
mmu:52040
|
| Nucleutide sequences |
EMBL-CDS:
BAC35301.1,
AAH29765.1,
AAH52059.1,
CAD44294.1
Ensembl_TRS:
ENSMUST00000087210,
ENSMUST00000087211
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000084461,
ENSMUSP00000084460
RefSeq:
XP_006524680.1,
XP_036016578.1,
XP_006524682.1,
XP_030105758.1,
NP_001344669.1,
NP_001157290.1,
XP_006524679.1
|
| Others |
UniRef100:
UniRef100_Q80W00
UniRef90:
UniRef90_Q96QC0
UniRef50:
UniRef50_Q96QC0
UniGene:
Mm.29385
CCDS:
CCDS50098.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30457570 |
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells. Sci Data Sunyuan Zhang , Nicholas A Williamson , Marie A Bogoyevitch |
2018-11-20 | - |
| 27034005 |
Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles. Oncotarget Anja E Eisenhardt , Adrian Sprenger , Michael Röring , Ricarda Herr , Florian Weinberg , Martin Köhler , Sandra Braun , Joachim Orth , Britta Diedrich , Ulrike Lanner , Natalja Tscherwinski , Simon Schuster , Nicolas Dumaz , Enrico Schmidt , Ralf Baumeister , Andreas Schlosser , Jörn Dengjel , Tilman Brummer |
2016-05-03 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 22083510 |
Oct4 links multiple epigenetic pathways to the pluripotency network. Cell Res. Junjun Ding , Huilei Xu , Francesco Faiola , Avi Ma'ayan , Jianlong Wang |
2012-01-01 |
Mfap1b,
Numa1,
Rpn1,
Rcor2,
Rfc4,
Scaf8,
Chd4,
Ogt,
Jmjd1c,
Tpr,
Lims1,
Supt16,
Parp1,
Mta3,
Ap2m1,
Aplp2,
Atp1a1,
Anxa2,
Calu,
Ctnnb1,
Serpinh1,
Cct2,
Cct3,
Cct4,
Cct5,
Cct7,
Cmas,
Cnn2,
Col18a1,
Csnk2a1,
Ctbp2,
Dbt,
Ddx4,
Dync1h1,
Eef2,
Wdr5,
Fen1,
Frg1,
Gfap,
Gli2,
Gnb1,
Gtf2i,
Hcfc1,
Hdgf,
Hells,
Hk2,
Hnrnpl,
Dnaja1,
Hspd1,
Hspg2,
Elavl1,
Idh3g,
Ilf3,
Ilk,
Kif11,
Kif4,
Lama1,
Lamb1,
Idh3b,
Matr3,
Mbd3,
Mcm5,
Mllt10,
Mllt4,
Msh2,
Msh6,
Naca,
Nedd4,
Sept2,
Nid2,
Orc2,
Otx2,
P4ha1,
Pcbp2,
Plk1,
Pou5f1,
Ppp1ca,
Ppp1cb,
Ppp1cc,
Prpf4b,
Flna,
Rad21,
Rfc1,
Upf1,
Dpf2,
Rnf2,
Rpn2,
Sf3a2,
Smarca4,
Smarcb1,
Smarcc1,
Ncor2,
Bptf,
Ssrp1,
Phf3,
Rbbp5,
Tbp,
Tfap2a,
Cdc73
|
| 20516061 |
Identification and characterization of a novel human PP1 phosphatase complex. J Biol Chem Jeong-Heon Lee , Jinsam You , Erika Dobrota , David G Skalnik |
2010-08-06 | - |
| 20372802 |
PNUTS knockdown potentiates the apoptotic effect of Roscovitine in breast and colon cancer cells. Int. J. Oncol. Gabriel De Leon , Margaret Cavino , Mikilyn D'Angelo , Nancy A Krucher |
2010-05-01 | - |
| 20360068 |
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science James R A Hutchins , Yusuke Toyoda , Björn Hegemann , Ina Poser , Jean-Karim Hériché , Martina M Sykora , Martina Augsburg , Otto Hudecz , Bettina A Buschhorn , Jutta Bulkescher , Christian Conrad , David Comartin , Alexander Schleiffer , Mihail Sarov , Andrei Pozniakovsky , Mikolaj Michal Slabicki , Siegfried Schloissnig , Ines Steinmacher , Marit Leuschner , Andrea Ssykor , Steffen Lawo , Laurence Pelletier , Holger Stark , Kim Nasmyth , Jan Ellenberg , Richard Durbin , Frank Buchholz , Karl Mechtler , Anthony A Hyman , Jan-Michael Peters |
2010-04-30 | - |
| 20412781 |
Dev. Cell Guoji Guo , Mikael Huss , Guo Qing Tong , Chaoyang Wang , Li Li Sun , Neil D Clarke , Paul Robson |
2010-04-20 |
Srcap,
Zbtb48,
Pds5b,
Dcun1d4,
Zfp513,
Zfp282,
Zfp956,
Zdhhc7,
Hinfp,
Zc3h10,
Etv5,
Isl2,
Rcor2,
Rhox9,
E2f4,
Mbnl2,
Cphx1,
Hmgxb3,
Ovol2,
Bmyc,
Jmjd6,
Gcm2,
Foxp1,
Ibtk,
Uhrf2,
Lmo1,
Cald1,
Dek,
Hivep1,
Lmx1a,
Lims1,
2610305D13Rik,
Foxp2,
Zbtb21,
Brdt,
Aebp2,
Nr0b1,
Ahr,
Aire,
Baz2a,
Mta3,
Ankfy1,
Nr2f2,
Klf16,
Arnt,
Arnt2,
Arntl,
Zfhx3,
Atf1,
Atf2,
Atf3,
Atf4,
Neurog3,
Bach1,
Bach2,
Bcl2l1,
Bcl3,
Prdm1,
Zfp36l1,
Zfp36l2,
Klf5,
Ctnnb1,
Runx2,
Runx3,
Cbx2,
Cdx1,
Cdx2,
Cdx4,
Cebpa,
Cited1,
Clock,
Creb3,
Atf6b,
Crem,
Crx,
Csrp1,
Csrp2,
Ctcf,
Cux1,
Cux2,
Dll1,
Dnmt1,
Dpm1,
Dr1,
Arid3a,
E2f1,
E2f5,
Ebf1,
Ebf3,
Phc1,
Egr1,
Ehf,
Elf1,
Elf3,
Elk1,
Epas1,
Nr2f1,
Erf,
Esr1
|
| 19287395 |
Nat. Struct. Mol. Biol. Hyeung Kim , Ok-Hee Lee , Huawei Xin , Liuh-Yow Chen , Jun Qin , Heekyung Kate Chae , Shiaw-Yih Lin , Amin Safari , Dan Liu , Zhou Songyang |
2009-04-01 |
TERF2,
MCPH1
|
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员