| Type | Description |
|---|---|
| Definition | PDZ binding kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:17:00 | Suppression of the solar ultraviolet-induced skin carcinogenesis by TOPK inhibitor HI-TOPK-032. | 32277233 |
| 2017-04-08 10:51:00 | this study shows that remote ischemic postconditioning protects against renal ischemia/reperfusion injury via activation of TOPK/PTEN/Akt signaling pathway | 27355132 |
| 2011-10-22 11:19:00 | T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein signaling pathway. | 21715333 |
| 2010-01-21 00:00:00 | The TOPK protein is expressed mainly in the cytosol of spermatocytes and spermatids, but not in spermatids and spermatogonia in situ. | 16316408 |
| 2010-01-21 00:00:00 | Melanoma cell lines expressing with high levels of TOPK are more resistant to As(3+)-induced apoptosis. Therefore, inhibition of TOPK activity combined with As(3+) treatment may be helpful in the treatment of melanomas. | 17145805 |
| Type | IDs |
|---|---|
| Synonymous | 2810434B10Rik, AW538537, D14Ertd732e, TOPK |
| Gene |
UniProtKB-ID:
TOPK_MOUSE
UniprotKB:
Q9JJ78
UniParc:
UPI0000021DC0
EMBL:
AK076121,
BC020099,
AK003838,
BC006754,
AB041882
Ensembl:
ENSMUSG00000022033
KO:
mmu:52033
|
| Nucleutide sequences |
EMBL-CDS:
AAH06754.1,
AAH20099.1,
BAA99578.1,
BAC36199.1,
BAB23029.1
Ensembl_TRS:
ENSMUST00000022612
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022612
RefSeq:
XP_006519320.1,
NP_075698.1
|
| Others |
UniRef100:
UniRef100_Q9JJ78
UniRef90:
UniRef90_Q9JJ78
UniRef50:
UniRef50_Q9JJ78
UniGene:
Mm.24337
CCDS:
CCDS27215.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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