| Type | Description |
|---|---|
| Definition | complement factor properdin |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:24:00 | Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement. | 32909942 |
| 2020-01-04 10:21:00 | TES-mediated upregulation of the transcription factor DDIT3 is involved in CFP suppression of breast cancer cell growth | 30755730 |
| 2019-11-23 11:15:00 | Study identified 2 single nucleotide polymorphisms, 1 in the mannose-binding lectin 2 gene (p.Gly54Asp-MBL2) and 1 in the complement factor properdin gene (p.Asn428(p=)-CFP), that showed significant association with the absence and development of antibody-mediated cardiac allograft rejection, respectively. | 28784323 |
| 2019-03-09 10:56:00 | Compound heterozygous mutations in IL10RA combined with a complement factor properdin mutation in infantile-onset inflammatory bowel disease. | 30199474 |
| 2018-04-14 10:36:00 | In conclusion, we challenge the view of properdin as a pattern recognition molecule by providing evidence that it binds to different exogenous and endogenous molecular patterns in only a C3-dependent manner. | 28069958 |
| Type | IDs |
|---|---|
| Synonymous | BFD, PFC, PFD, PROPERDIN |
| Gene |
UniProtKB-ID:
PROP_HUMAN,
A0A0S2Z4I5_HUMAN
UniprotKB:
P27918,
A0A0S2Z4I5
UniParc:
UPI0000132325
EMBL:
M83652,
AY297813,
X57748,
X70872,
AF005664,
AF005665,
KU178249,
AF005667,
AF005668,
CH471164,
BC015756,
AF005666,
AL009172
Ensembl:
ENSG00000126759
KO:
hsa:5199
|
| Nucleutide sequences |
EMBL-CDS:
AAB62886.1,
AAH15756.1,
AAP43692.1,
AAB63279.1,
AAC51626.1,
CAA40914.1,
AAB63280.1,
CAA50220.1,
AAA36489.1,
EAW59320.1,
ALQ33707.1
Gene_ORFName:
hCG_29138
Ensembl_TRS:
ENST00000396992,
ENST00000247153
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000380189,
ENSP00000247153
RefSeq:
NP_002612.1,
NP_001138724.1,
XP_016885064.1
|
| Others |
UniRef100:
UniRef100_P27918
UniRef90:
UniRef90_P27918
UniRef50:
UniRef50_P27918
UniGene:
Hs.53155
CCDS:
CCDS14282.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员