| Type | Description |
|---|---|
| Definition | platelet factor 4 variant 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 11:33:00 | CXCL4L1 promoter variants may protect against the development of renal inflammation in diabetes by increasing CXCL4L1 expression, which in turn activates the anti-inflammatory SMAD7 and IkappaBalpha factors in mesangial cells. | 30593538 |
| 2019-10-26 10:39:00 | CXCL4 and CXCL4L1 shift the angiogenic/angiostatic balance in favor of angiostasis. CXCL4L1 in particular was found to be a more potent angiostatic, anti-tumoral and anti-metastatic chemokine, which was verified in different in vivo models. | 29903575 |
| 2015-10-26 16:26:00 | Fibstatin and CXCL4L1 cooperate to inhibit endothelial cell proliferation, migration and tubulogenesis in vitro. | 23747987 |
| 2015-02-07 11:43:00 | CXCL4 and CXCL4L1 activated p38 MAPK, as well as Src kinase within 30 and 5 min, respectively. Extracellular signal-regulated kinase (ERK) phosphorylation occurred in activated lymphocytes. | 24469069 |
| 2014-03-29 11:21:00 | fibstatin and CXCL4L1 have cooperative roles in inhibition of tumor invasion in lymph nodes | 23747987 |
| Type | IDs |
|---|---|
| Synonymous | CXCL4L1, CXCL4V1, PF4-ALT, PF4A, SCYB4V1 |
| Gene |
UniProtKB-ID:
PF4V_HUMAN
UniprotKB:
P10720
UniParc:
UPI000013171A
EMBL:
M26167,
BC130657,
CH471057,
BC130653
Ensembl:
ENSG00000109272
KO:
hsa:5197
|
| Nucleutide sequences |
EMBL-CDS:
AAI30658.1,
EAX05692.1,
AAI30654.1,
AAA60067.1
Ensembl_TRS:
ENST00000226524
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000226524
RefSeq:
NP_002611.1
|
| Others |
UniRef100:
UniRef100_P10720
UniRef90:
UniRef90_P10720
UniRef50:
UniRef50_P10720
UniGene:
Hs.72933
CCDS:
CCDS3561.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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