| Type | Description |
|---|---|
| Definition | peroxisomal biogenesis factor 14 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:06:00 | Mitotic phosphorylation of Pex14p regulates peroxisomal import machinery. | 32854114 |
| 2017-09-30 13:36:00 | Data suggest that soluble/cytosolic PEX5 interacts with PEX14/PEX13 complex, a model for the docking/translocation module (DTM) of the peroxisomal matrix protein translocon; PEX14/PEX13 complex appears to function in peroxisomal membrane as large cavity into which cytosolic PEX5 can enter to release its cargo. (PEX = peroxisomal biogenesis factor) | 28765278 |
| 2017-05-06 10:44:00 | data reveal subpopulations of peroxisomes showing only weak colocalization between PEX14 and PEX5 or PEX11 but at the same time a clear compartmentalized organization. This compartmentalization, which was less evident in cases of strong colocalization, indicates dynamic protein reorganization linked to changes occurring in the peroxisomes. | 27311714 |
| 2017-01-28 10:18:00 | PEX14 is the 13th PEX gene responsible for peroxisome biogenesis disorders. Thus far, only two patients with PEX14 deficiency have been reported. | 26627464 |
| 2014-03-22 10:04:00 | The novel Pex14-binding site may represent the initial tethering site of Pex5 from which the cargo-loaded receptor is further processed in a sequential manner. | 24235149 |
| Type | IDs |
|---|---|
| Synonymous | NAPP2, PBD13A, Pex14p, dJ734G22.2 |
| Gene |
UniProtKB-ID:
PEX14_HUMAN
UniprotKB:
O75381
UniParc:
UPI000013170A,
UPI0000E1E62B
EMBL:
AK002194,
AL354956,
AF045186,
AK293684,
CR450321,
AB017546,
AK313046,
CR542083,
AL139423,
AL591403,
BC006327,
CH471130
Ensembl:
ENSG00000142655
KO:
hsa:5195
|
| Nucleutide sequences |
EMBL-CDS:
AAH06327.1,
CAG29317.1,
AAC39843.1,
CAG46880.1,
BAG51028.1,
BAG35878.1,
EAW71661.1,
BAA36837.1,
BAH11568.1
Ensembl_TRS:
ENST00000356607
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000349016
RefSeq:
XP_011539879.1,
XP_011539880.1,
XP_011539882.1,
XP_024303419.1,
NP_004556.1,
XP_005263527.1,
XP_011539881.1
|
| Others |
UniRef100:
UniRef100_O75381
UniRef90:
UniRef90_O75381
UniRef50:
UniRef50_O75381
UniGene:
Hs.149983
CCDS:
CCDS30582.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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