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5194 PEX13

5194

PEX13

peroxisomal biogenesis factor 13

protein-coding

Homo sapiens

基因描述

Type Description
Definition peroxisomal biogenesis factor 13

研究结论

Date Results Publications
2020-12-12 13:22:00 Hepatocyte-specific deletion of peroxisomal protein PEX13 results in disrupted iron homeostasis. 32565019
2017-09-30 13:36:00 Data suggest that soluble/cytosolic PEX5 interacts with PEX14/PEX13 complex, a model for the docking/translocation module (DTM) of the peroxisomal matrix protein translocon; PEX14/PEX13 complex appears to function in peroxisomal membrane as large cavity into which cytosolic PEX5 can enter to release its cargo. (PEX = peroxisomal biogenesis factor) 28765278
2017-08-19 12:04:00 our results demonstrate that PEX13 is required for selective autophagy, and suggest that dysregulation of PEX13-mediated mitophagy may contribute to ZSS pathogenesis. 27827795
2014-03-22 11:40:00 Results show PEX13 interacts with itself in peroxisomes in living cells and the import of PTS1 (peroxisomal targeting signal 1) proteins is specifically disrupted when homooligomerization of PEX13 is interrupted. 23716570
2010-01-21 00:00:00 Zellweger syndrome caused by PEX13 deficiency: report of two novel mutations. 19449432

名称对应

Type IDs
Synonymous NALD, PBD11A, PBD11B, ZWS
Gene
UniProtKB-ID: PEX13_HUMAN
UniprotKB: Q92968
UniParc: UPI0000131707
EMBL: U71374, AK315244, CH471053, AF048755, AB022192, BC067090
Ensembl: ENSG00000162928
KO: hsa:5194
Nucleutide sequences
EMBL-CDS: BAA88907.1, EAX00018.1, AAD05572.1, AAH67090.1, AAC39844.1, BAG37668.1
Ensembl_TRS: ENST00000295030
Protein sequencees
Ensembl_PRO: ENSP00000295030
RefSeq: NP_002609.1
Others
UniRef100: UniRef100_Q92968
UniRef90: UniRef90_Q92968
UniRef50: UniRef50_Q92968
UniGene: Hs.161377
CCDS: CCDS1866.1

全选

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