| Type | Description |
|---|---|
| Definition | peroxisomal biogenesis factor 7 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-12 12:11:00 | Data suggest that P7BP2 is localized to peroxisomes by binding to PEX5 via PEX7 in manner dependent on apparent PTS2 (type 2 peroxisomal targeting signal peptide) in N-terminal region of P7BP2; the PTS2 is subsequently cleaved off in peroxisomes. (P7BP2 = PEX7-binding protein-2; PEX5 = peroxisomal biogenesis factor-5; PEX7 = peroxisomal biogenesis factor-7) | 30204880 |
| 2017-06-24 10:55:00 | This revealed a marked plasmalogen deficiency and a deficient fatty acid alpha-oxidation in the IHH cells, due to a defect of PEX7, a cytosolic receptor protein required for peroxisomal import of a subset of peroxisomal proteins. | 28013369 |
| 2016-08-06 11:47:00 | our data suggest that insertion of the trimeric PEX5-PEX7-PTS2 protein complex into the DTM is probably accompanied by conformational alterations in PEX5 to allow release of the PTS2 protein into the organelle matrix | 26138649 |
| 2016-03-26 10:43:00 | Mutation in the PEX7 Gene is associated with Rhizomelic Chondrodysplasia Punctata Type 1. | 25800479 |
| 2015-05-09 12:38:00 | the sequential formation of a highly stable trimeric complex involving cargo protein, PEX7 and PEX5L stabilizes cargo binding and is a prerequisite for PTS2-mediated peroxisomal import. | 25538232 |
| Type | IDs |
|---|---|
| Synonymous | PBD9B, PTS2R, RCDP1, RD |
| Gene |
UniProtKB-ID:
PEX7_HUMAN,
Q6FGN1_HUMAN
UniprotKB:
O00628,
Q6FGN1
UniParc:
UPI0000073043,
UPI00001316F3
EMBL:
CH471051,
AF180806,
BC006268,
AF180807,
U76560,
CR542054,
BC031606,
AF180812,
AF180810,
AF180813,
AF180808,
AF180811,
AL365223,
AF180814,
AF180809,
AL121933,
CR542076,
U88871,
AL357082
Ensembl:
ENSG00000112357
KO:
hsa:5191
|
| Nucleutide sequences |
EMBL-CDS:
AAH31606.1,
AAB50556.1,
AAF37350.1,
EAW47941.1,
AAC51238.1,
AAH06268.1,
EAW47940.1,
CAG46851.1,
CAG46873.1
Gene_ORFName:
hCG_1640802
Ensembl_TRS:
ENST00000318471,
ENST00000541292
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000315680,
ENSP00000441004
RefSeq:
XP_006715565.1,
XP_005267076.1,
XP_016866423.1,
NP_000279.1
|
| Others |
UniRef100:
UniRef100_O00628
UniRef90:
UniRef90_O00628
UniRef50:
UniRef50_O00628
UniGene:
Hs.280932
CCDS:
CCDS5180.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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