| Type | Description |
|---|---|
| Definition | dimethylarginine dimethylaminohydrolase 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-04 10:47:00 | the overexpression of DDAH2 attenuates myocardial fibrosis and protects against Diabetic cardiomyopathy DCM through activation of the DDAH/ADMA/NOS/NO pathway | 30569164 |
| 2017-12-16 12:06:00 | We conclude that pp60(Src) can directly inhibit DDAH II and this is involved in the increased ADMA levels that enhance eNOS uncoupling during the development of acute lung injury (ALI). | 27838434 |
| 2016-10-22 10:27:00 | In mild CKD, dysregulation of the ADMA/DDAH pathway in adipose tissue triggers lipodystrophy-like phenotype changes, including ectopic fat depositions. | 26516203 |
| 2013-08-03 10:29:00 | The Sirt1/DDAH2/secretagogin pathway is a novel regulator of glucose-stimulated insulin secretion. | 23430976 |
| 2010-01-21 00:00:00 | DDAH2/ADMA pathway can be a novel therapeutic target for vasculopathy in the ADMA or angiotensin II-induced pathophysiological conditions | 17601800 |
| Type | IDs |
|---|---|
| Synonymous | 1110003M04Rik, AU019324, AW413173, DDAH-2, DDAHII, Ddah, G6a, NG30 |
| Gene |
UniProtKB-ID:
DDAH2_MOUSE,
O08972_MOUSE
UniprotKB:
Q99LD8,
O08972
UniParc:
UPI00000E6B54,
UPI0000027DA3
EMBL:
AC087117,
BC003328,
AF109905,
AF004106
Ensembl:
ENSMUSG00000007039
KO:
mmu:51793
|
| Nucleutide sequences |
EMBL-CDS:
AAH03328.1,
AAC84156.1,
AAC16251.1
Ensembl_TRS:
ENSMUST00000007255,
ENSMUST00000174493
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000007255,
ENSMUSP00000134072
RefSeq:
NP_058045.1,
XP_006524675.1,
NP_001177378.1,
XP_030105756.1
|
| Others |
UniRef100:
UniRef100_Q99LD8,
UniRef100_O08972
UniRef90:
UniRef90_A0A4X1VDQ7,
UniRef90_Q6MG60
UniRef50:
UniRef50_O95865,
UniRef50_Q3SX44
UniGene:
Mm.1457
CCDS:
CCDS50082.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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