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5178 PEG3

5178

PEG3

paternally expressed 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition paternally expressed 3

研究结论

Date Results Publications
2021-04-03 13:37:00 PEG3 mutation is associated with elevated tumor mutation burden and poor prognosis in breast cancer. 32729618
2020-06-20 11:51:00 These key findings demonstrated that upregulation of ZNF667-AS1 could suppress the progression of cervical cancer via the modulation of miR-93-3p-dependent PEG3. 31420931
2019-06-22 10:19:00 Soluble matrix-derived cues being transduced downstream of receptor engagement converge upon a newly-discovered nexus of autophagic machinery consisting of Peg3 for endothelial cell autophagy and mitostatin for tumor cell mitophagy. 29080840
2019-04-27 11:47:00 Peg3 expression levels anti-correlate with pluripotency and increase gradually upon ESC differentiation. Moreover, downregulation of Peg3 enhances the efficiency of reprogramming of differentiated cells towards pluripotency. 28852087
2017-10-21 11:59:00 Data suggest that PEG3 is required for TFEB induction and nuclear translocation in a VEGFR2- and AMPK-dependent manner for decorin/decorin receptor-evoked autophagy. (PEG3 = paternally expressed 3 protein; TFEB = transcription factor EB; VEGFR2 = vascular endothelial growth factor receptor-2; AMPK = AMP-activated protein kinase) 28798237

名称对应

Type IDs
Synonymous PW1, ZKSCAN22, ZNF904, ZSCAN24
Gene
UniProtKB-ID: PEG3_HUMAN, Q96Q96_HUMAN
UniprotKB: Q9GZU2, Q96Q96
UniParc: UPI0000DD095F, UPI000006D36D, UPI0000072D02, UPI000006EC0E, UPI000059D7BE
EMBL: AB006625, AF208976, U90336, AK295679, AF208967, BC052616, AF208969, AF208980, AF208970, CR933682, AF208979, AF208975, AF208968, AB003039, AF208974, BC150272, AC006115, AF208978, CH471135, AF208977
Ensembl: ENSG00000198300
KO: hsa:5178
Nucleutide sequences
EMBL-CDS: AAC83176.1, BAG58536.1, AAG35740.1, CAI45975.1, AAG42324.1, AAG35741.1, AAB50011.1, EAW72474.1, AAG42325.1, AAG35739.1, BAB85588.1, AAH52616.1, AAI50273.1, AAG35742.1, BAA22956.2
Ensembl_TRS: ENST00000648694, ENST00000599534, ENST00000326441, ENST00000649876, ENST00000650102, ENST00000649680, ENST00000650632, ENST00000649233, ENST00000599577, ENST00000649428, ENST00000593695, ENST00000598410
Protein sequencees
Ensembl_PRO: ENSP00000473190, ENSP00000472402, ENSP00000326581, ENSP00000497971, ENSP00000472395, ENSP00000497466, ENSP00000496867, ENSP00000496914, ENSP00000469486, ENSP00000498047, ENSP00000497512, ENSP00000498138
RefSeq: NP_001356661.1, NP_001356659.1, NP_001356651.1, NP_001356646.1, NP_001356662.1, NP_001356652.1, NP_001356647.1, NP_001356660.1, NP_001356650.1, NP_001356667.1, NP_001356665.1, NP_001356664.1, NP_001139657.1, NP_001139656.1, NP_001356649.1, NP_001356668.1, NP_001356666.1, NP_001356658.1, NP_001356657.1, NP_001139659.1, NP_006201.1, NP_001356656.1, NP_001356648.1, NP_001356663.1, NP_001356654.1, NP_001356653.1, NP_001356655.1
Others
UniRef100: UniRef100_Q96Q96, UniRef100_Q9GZU2
UniRef90: UniRef90_Q9GZU2
UniRef50: UniRef50_Q9GZU2
UniGene: Hs.731875
CCDS: CCDS12948.1, CCDS58684.1, CCDS58685.1

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