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51765 STK26

51765

STK26

serine/threonine kinase 26

protein-coding

Homo sapiens

基因描述

Type Description
Definition serine/threonine kinase 26

研究结论

Date Results Publications
2021-02-20 13:29:00 MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway. 32271880
2021-01-09 13:30:00 Downregulation of MST4 Underlies a Novel Inhibitory Role of MicroRNA Let-7a in the Progression of Retinoblastoma. 32539131
2020-10-10 12:57:00 MicroRNA-486-5p inhibits ovarian granulosa cell proliferation and participates in the development of PCOS via targeting MST4. 31539108
2020-03-21 11:52:00 The expression of three genes (STK26, KCNT2, CASP12) was correlated with the prognosis of skin cutaneous melanoma (SCM). STK26 and KCNT2 were significantly different between normal skin and SCM. These three hub genes have potential value as predictors for accurate diagnosis and prognosis of SCM in the future. 31557882
2019-04-13 12:23:00 Because of divergent evolution of key interface residues, MST4 and MOB4 could disrupt assembly of the MST1-MOB1 complex through alternative pairing and thereby increased YAP activity. Collectively, these findings identify the MST4-MOB4 complex as a noncanonical regulator of the Hippo-YAP pathway with an oncogenic role in PC 30072378

名称对应

Type IDs
Synonymous MASK, MST4
Gene
UniProtKB-ID: STK26_HUMAN
UniprotKB: Q9P289
UniParc: UPI0000030CB8, UPI000006D6B3, UPI0000071EAD
EMBL: BC098315, AK314356, CH471107, AF231012, AF344882, BC103503, AK075107, BT020099, AF344883, AL109749, AB040057
Ensembl: ENSG00000134602
KO: hsa:51765
Nucleutide sequences
EMBL-CDS: AAV38902.1, BAA92785.2, AAK29621.1, AAK29620.1, AAI03504.1, EAX11787.1, AAK38484.1, EAX11786.1, BAC11406.1, AAH98315.1, BAG36989.1
Ensembl_TRS: ENST00000496850, ENST00000394334, ENST00000394335
Protein sequencees
Ensembl_PRO: ENSP00000419702, ENSP00000377868, ENSP00000377867
RefSeq: XP_011529652.1, XP_011529651.1, NP_001035918.1, NP_001035917.1, NP_057626.2
Others
UniRef100: UniRef100_Q9P289
UniRef90: UniRef90_Q9P289
UniRef50: UniRef50_Q9P289
UniGene: Hs.444247
CCDS: CCDS48168.1, CCDS14631.1, CCDS43995.1

全选

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