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51755 CDK12

51755

CDK12

cyclin dependent kinase 12

protein-coding

Homo sapiens

基因描述

Type Description
Definition cyclin dependent kinase 12

研究结论

Date Results Publications
2021-04-03 13:35:00 Low expression of CDK12 in gastric cancer is correlated with advanced stage and poor outcome. 32534699
2021-03-06 13:33:00 CDK12: A Potent Target and Biomarker for Human Cancer Therapy. 32570740
2021-02-27 13:45:00 Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation. 32804079
2021-01-02 12:53:00 CDK12 and HER2 coamplification in two urothelial carcinomas with rapid and aggressive clinical progression. 33038052
2020-09-26 13:09:00 CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation. 32805052

名称对应

Type IDs
Synonymous CRK7, CRKR, CRKRS
Gene
UniProtKB-ID: CDK12_HUMAN
UniprotKB: Q9NYV4
UniParc: UPI0001AE6620, UPI00005785C5, UPI000013E688
EMBL: AK302645, AF227198, AB020711, AC009283, BC150265, BC140854, CH471152
Ensembl: ENSG00000167258
KO: hsa:51755
Nucleutide sequences
EMBL-CDS: BAG63886.1, BAA74927.2, AAI40855.1, EAW60577.1, AAF36401.1, AAI50266.1
Ensembl_TRS: ENST00000430627, ENST00000447079
Protein sequencees
Ensembl_PRO: ENSP00000398880, ENSP00000407720
RefSeq: XP_011523194.1, XP_005257515.1, XP_011523199.1, XP_011523196.1, NP_057591.2, XP_011523208.1, XP_016880241.1, XP_011523200.1, XP_016880242.1, XP_016880239.1, XP_011523205.1, XP_011523197.1, XP_011523201.1, XP_016880236.1, XP_005257513.1, XP_011523207.1, XP_011523204.1, XP_016880237.1, XP_016880238.1, XP_011523202.1, XP_011523198.1, XP_024306569.1, XP_016880240.1, XP_011523209.1, XP_011523203.1, XP_011523195.1, NP_055898.1
Others
UniRef100: UniRef100_Q9NYV4
UniRef90: UniRef90_Q9NYV4
UniRef50: UniRef50_Q9NYV4
UniGene: Hs.416108
CCDS: CCDS11337.1, CCDS45666.1

全选

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