| Type | Description |
|---|---|
| Definition | PDZ domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 12:59:00 | Long noncoding RNA PENG upregulates PDZK1 expression by sponging miR-15b to suppress clear cell renal cell carcinoma cell proliferation. | 32341409 |
| 2020-06-06 10:23:00 | Sun exposure and PDZK1 genotype modulate PDZK1 gene expression in normal skin. | 31444921 |
| 2020-03-28 10:13:00 | Low levels of PDZK1 in gastric cancer specimens lead to increase proliferation of gastric cancer cells via phosphorylation of PTEN at the S380/T382/T383 cluster and constitutively activation of PI3K/AKT signaling, which results in poor prognosis of gastric cancer patients. | 30930234 |
| 2019-09-28 12:40:00 | Results find that PDZK1 has a defined, extended, and L-shaped conformation in solution. The non-PDZ regions of PDZK1 play a key role in supporting a defined conformation; the fourth PDZ domain of PDZK1 also binds to the C terminus of PEPT2. | 30220543 |
| 2019-08-31 10:56:00 | LXRalpha and PXR are transcriptional regulators of PDZK1. | 30831268 |
| Type | IDs |
|---|---|
| Synonymous | CAP70, CLAMP, NHERF-3, NHERF3, PDZD1 |
| Gene |
UniProtKB-ID:
NHRF3_HUMAN
UniprotKB:
Q5T2W1
UniParc:
UPI000006D202,
UPI0001AE78C3
EMBL:
AL390725,
AK298269,
BC006518,
AF012281,
BC006496
Ensembl:
ENSG00000174827
KO:
hsa:5174
|
| Nucleutide sequences |
EMBL-CDS:
BAG60531.1,
AAC12264.1,
AAH06496.1,
AAH06518.1,
CAI13715.1,
CAI13716.1
Ensembl_TRS:
ENST00000417171,
ENST00000451928,
ENST00000344770
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000403422,
ENSP00000394485,
ENSP00000342143
RefSeq:
NP_002605.2,
XP_011507918.2,
NP_001188255.1,
XP_024303384.1,
NP_001358290.1,
XP_024303387.1,
NP_001358288.1,
XP_016856956.1,
XP_024303388.1,
NP_001188254.1
|
| Others |
UniRef100:
UniRef100_Q5T2W1
UniRef90:
UniRef90_Q5T2W1
UniRef50:
UniRef50_Q5T2W1
UniGene:
Hs.444751,
Hs.732345
CCDS:
CCDS72860.1,
CCDS72859.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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