| Type | Description |
|---|---|
| Definition | Rap guanine nucleotide exchange factor 6 |
| Date | Results | Publications |
|---|---|---|
| 2015-06-20 11:15:00 | local accumulation of PDZGEF at the apical membrane during establishment of epithelial polarity is mediated by electrostatic interactions between positively charged side chains in the PDZ domain and negatively charged phosphatidic acid. | 24858808 |
| 2010-10-23 11:13:00 | BAG3 overexpression increases cell adhesion in Cos7 cells, but not in PDZGEF2 gene knockdown cells indicating that PDZGEF2 is a critical partner for BAG3 in regulating cell adhesion | 20800573 |
| 2010-01-21 00:00:00 | JAM-A dimerization facilitates formation of a complex with Afadin and PDZ-GEF2 that activates Rap1A, which regulates beta1 integrin levels and cell migration. | 19176753 |
| 2010-01-21 00:00:00 | haplotypes underlying the SPEC2/PDZ-GEF2/acyl-CoA synthetase long-chain family member 6 region are associated with schizophrenia | 17030554 |
| 2010-01-21 00:00:00 | When males and females were analysed separately, SNP4 (rs31251) in PDZ-GEF2 is associated with schizophrenia in females in Han Chinese. | 18718982 |
| Type | IDs |
|---|---|
| Synonymous | KIA001LB, PDZ-GEF2, PDZGEF2, RA-GEF-2, RAGEF2 |
| Gene |
UniProtKB-ID:
RPGF6_HUMAN,
B2RTU6_HUMAN
UniprotKB:
Q8TEU7,
B2RTU6
UniParc:
UPI000189A836,
UPI0001B25605,
UPI0000F3B8F0,
UPI000013EC9D,
UPI0000EE35ED,
UPI000020C537,
UPI0001B25606
EMBL:
AF478469,
AC008695,
AC008497,
BC144627,
BC142964,
AF478468,
AC026754,
BC133703,
BC140820,
CH471062,
AC004227,
AC004622,
AF394782,
AF478567
Ensembl:
ENSG00000158987
KO:
hsa:51735
|
| Nucleutide sequences |
EMBL-CDS:
AAL79916.1,
AAM21637.1,
AAI44628.1,
AAI33704.1,
AAI42965.1,
AAK83368.1,
AAL79915.1,
AAI40821.1,
EAW62367.1
Gene_ORFName:
hCG_1981012
Ensembl_TRS:
ENST00000296859,
ENST00000507093,
ENST00000510071,
ENST00000509018,
ENST00000627212,
ENST00000308008
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296859,
ENSP00000421684,
ENSP00000426081,
ENSP00000487439,
ENSP00000425389,
ENSP00000311419
RefSeq:
NP_001157860.1,
NP_001157858.1,
NP_057424.3,
NP_001157861.1,
NP_001157862.1,
NP_001157859.1
|
| Others |
UniRef100:
UniRef100_B2RTU6,
UniRef100_Q8TEU7
UniRef90:
UniRef90_Q8TEU7-4,
UniRef90_Q8TEU7
UniRef50:
UniRef50_Q8TEU7
UniGene:
Hs.483329
CCDS:
CCDS54898.1,
CCDS54900.1,
CCDS54901.1,
CCDS34225.1,
CCDS54899.1,
CCDS54897.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员