| Type | Description |
|---|---|
| Definition | methionine sulfoxide reductase B1 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-24 10:51:00 | In vivo, MsrB1 can inhibit lung metastasis in metastasis model. In conclusion, MsrB1 regulates proliferation and invasion of u2os cells by affecting MAPK pathway and EMT, and MsrB1 gene may be a novel therapeutic target against tumors. | 29395081 |
| 2017-10-07 12:04:00 | FRET and co-IP assays demonstrated that Clu interacted with beta-amyloid peptide, a pathological protein of AD, which suggested a potential effect of SelR and Abeta with the aid of Clu. The interaction between SelR and Clu provides a novel avenue for further study on the mechanism of SelR in AD prevention. | 23805218 |
| 2017-05-08 13:02:00 | MsrB1 protected human lens epithelial cells against the peroxynitrite-induced F-actin disruption. | 24342607 |
| 2017-01-28 11:46:00 | findings suggested that SelX played important roles in protecting LO2 cells against oxidative damage and reducing H2O2-induced apoptosis in liver cells. | 26899321 |
| 2016-11-05 10:41:00 | Selenoprotein R Protects Human Lens Epithelial Cells against D-Galactose-Induced Apoptosis by Regulating and Stress | 26875981 |
| Type | IDs |
|---|---|
| Synonymous | HSPC270, SELR, SELX, SEPX1, SepR |
| Gene |
UniProtKB-ID:
MSRB1_HUMAN
UniprotKB:
Q9NZV6
UniParc:
UPI0000161C13
EMBL:
AF161388,
AC005363,
AF166124,
BC003127,
AF187272,
AE006640
Ensembl:
ENSG00000198736
KO:
hsa:51734
|
| Nucleutide sequences |
EMBL-CDS:
AAK61300.1,
AAG17033.1,
AAF28948.1,
AAH03127.2,
AAF21429.1
Gene_ORFName:
HSPC270
Ensembl_TRS:
ENST00000361871
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355084
RefSeq:
NP_057416.1,
NP_001369194.1,
NP_001369193.1
|
| Others |
UniRef100:
UniRef100_Q9NZV6
UniRef90:
UniRef90_Q9NZV6
UniRef50:
UniRef50_Q9NZV6
UniGene:
Hs.655346
CCDS:
CCDS42100.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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