Type | Description |
---|---|
Definition | DnaJ heat shock protein family (Hsp40) member B11 |
Date | Results | Publications |
---|---|---|
2020-07-18 11:31:00 | These findings suggest that, under normal conditions, ERdj3 functions as an ER chaperone in complex with SDF2/SDF2L1 but is secreted into the extracellular space when it cannot form this complex. | 31624144 |
2019-05-18 12:12:00 | strong positive expression of DNAJB11 was an independent prognostic factor for disease-free survival and overall survival in epithelial ovarian cancer | 28752709 |
2019-04-20 12:03:00 | ERdj3 expression is enhanced in hepatocellular carcinoma (HCC) tumors and is positively associated with more inferior survival outcomes. ERdj3 promotes intracellular Z mutant of alpha-1-antitrypsin (AATZ) accumulation in HCC cells via suppressing post-transcriptional AATZ degradation and promotes HCC cell proliferation, epithelial-mesenchymal transition, migratory ability and invasiveness in an AATZ-dependent manner. | 29992839 |
2018-12-22 10:13:00 | DNAJB11-associated disease is a phenotypic hybrid of Autosomal-dominant polycystic kidney disease and autosomal-dominant tubulointerstitial diseases. | 29706351 |
2017-12-23 12:56:00 | ZAAT ER clearance resulted from enhancing ERdj3-mediated ZAAT degradation by silencing ERdj3 while simultaneously enhancing autophagy. In this context, ERdj3 suppression may eliminate the toxic gain of function associated with polymerization of ZAAT | 28419579 |
Type | IDs |
---|---|
Synonymous | ABBP-2, ABBP2, DJ9, Dj-9, EDJ, ERdj3, ERj3, ERj3p, PKD6, PRO1080, UNQ537 |
Gene |
UniProtKB-ID:
DJB11_HUMAN
UniprotKB:
Q9UBS4
UniParc:
UPI0000001BF7
EMBL:
AY359043,
AJ250137,
CR457096,
AB028859,
AF277317,
AF228505,
AK075430,
CH471052,
BT007063,
BC001144,
AK075300
Ensembl:
ENSG00000090520
KO:
hsa:51726
|
Nucleutide sequences |
EMBL-CDS:
CAG33377.1,
AAF61711.1,
AAP35712.1,
CAB65118.1,
AAQ89402.1,
AAH01144.1,
BAA88307.1,
AAK69110.1,
EAW78190.1,
BAC11617.1,
BAC11533.1
Gene_ORFName:
UNQ537/PRO1080,
PSEC0121
Ensembl_TRS:
ENST00000265028,
ENST00000439351
|
Protein sequencees |
Ensembl_PRO:
ENSP00000265028,
ENSP00000414398
RefSeq:
NP_057390.1,
NP_001365380.1
|
Others |
UniRef100:
UniRef100_Q9UBS4
UniRef90:
UniRef90_Q9UBS4
UniRef50:
UniRef50_Q9UBS4
UniGene:
Hs.317192
CCDS:
CCDS3277.1
|
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