| Type | Description |
|---|---|
| Definition | cleavage and polyadenylation specific factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 12:29:00 | CPSF3 represents a synthetic lethal node in a subset of acute myeloid leukemia and Ewing's sarcoma cancer cell lines | 31819276 |
| 2019-12-07 11:06:00 | CASC9 is a promising prognostic predictor for patients with CRC and the CASC9-CPSF3-TGFbeta2 axis is a potential therapeutic target for CRC treatment. | 31186036 |
| 2013-04-27 12:09:00 | the molecular mechanism that recruits the CPSF73 endonuclease to histone pre-mRNAs | 23071092 |
| 2011-01-15 10:49:00 | The data support a model where Star-PAP binds to the pre-mRNA, recruits the CPSF complex to the 3'-end of pre-mRNA and then defines cleavage by CPSF 73 and subsequent polyadenylation of its target mRNAs. | 21102410 |
| 2010-01-21 00:00:00 | up-regulated by HIV-1 TAT protein; this could represent a novel mechanism by which HIV increases mRNA processing, causing an increase in both cell and viral gene expression. | 15194760 |
| Type | IDs |
|---|---|
| Synonymous | CPSF-73, CPSF73 |
| Gene |
UniProtKB-ID:
CPSF3_HUMAN,
G5E9W3_HUMAN
UniprotKB:
Q9UKF6,
G5E9W3
UniParc:
UPI00001282F5,
UPI0000EE22F1
EMBL:
BC020211,
AC080162,
AF017269,
AF171877,
BC011654,
CH471053
Ensembl:
ENSG00000119203
KO:
hsa:51692
|
| Nucleutide sequences |
EMBL-CDS:
EAX00989.1,
AAY14858.1,
AAH20211.1,
AAH11654.1,
AAF00224.1,
AAB70268.1,
EAX00990.1
Gene_ORFName:
hCG_1784298
Ensembl_TRS:
ENST00000238112,
ENST00000460593
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000238112,
ENSP00000418957
RefSeq:
NP_001308764.1,
NP_001308763.1,
NP_001308765.1,
NP_057291.1,
NP_001308762.1
|
| Others |
UniRef100:
UniRef100_G5E9W3,
UniRef100_Q9UKF6
UniRef90:
UniRef90_I3LKR1,
UniRef90_Q9UKF6
UniRef50:
UniRef50_Q9UKF6,
UniRef50_F7E4T0
UniGene:
Hs.515972
CCDS:
CCDS1664.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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