| Type | Description |
|---|---|
| Definition | negative regulator of ubiquitin like proteins 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 11:49:00 | Authors created a series of phosphomimic mutants of NUB1 and found that phosphorylation of NUB1 at S46 (P-NUB46) efficiently degrades aggregates using a cell-based assay. | 31006160 |
| 2017-08-12 10:19:00 | Mdm2 acts as a positive regulator of NUB1 function, by modulating NUB1 ubiquitination on lysine 159. | 28099510 |
| 2017-04-29 10:36:00 | data suggest that NUB1 participates in telomere maintenance by regulating the levels of TRF1 at telomeres through both NEDD8-dependent and NEDD8-independent pathways. | 27214791 |
| 2015-12-19 10:11:00 | NUB1L suppresses atypical neddylation and promotes the degradation of misfolded proteins by the proteasome | 26260793 |
| 2014-02-22 11:47:00 | Based on biochemical features of the VBM motifs, we also identified NUB1L (NEDD8 ultimate buster-1 long) as a novel VBM-containing protein, which is involved in proteasomal degradation of NEDD8 through the P97 pathway. | 24100225 |
| Type | IDs |
|---|---|
| Synonymous | BS4, NUB1L, NYREN18 |
| Gene |
UniProtKB-ID:
NUB1_HUMAN,
H3BM14_HUMAN,
H3BM74_HUMAN,
A0A090N8Q5_HUMAN
UniprotKB:
Q9Y5A7,
H3BM14,
H3BM74,
A0A090N8Q5
UniParc:
UPI000007442B,
UPI000000DB71,
UPI00021CF908,
UPI0000D48BD3
EMBL:
AACC02000108,
BC046354,
CH471173,
AF155099,
AF108083,
KF458635,
AY129295,
KF458638,
AC005486,
AF459743,
AF300717
Ensembl:
ENSG00000013374
KO:
hsa:51667
|
| Nucleutide sequences |
EMBL-CDS:
AAN01355.1,
AAD42865.1,
AAO14547.1,
AAK21001.1,
AAS02030.1,
AAH46354.1,
AAC82474.2,
EAW54003.1,
EAL24511.1
Gene_ORFName:
hCG_19587,
tcag7.767
Ensembl_TRS:
ENST00000470229,
ENST00000413040,
ENST00000568733
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000418234,
ENSP00000398644,
ENSP00000454264
RefSeq:
XP_016867793.1,
NP_001372284.1,
NP_001230280.2,
XP_016867797.1,
XP_024302567.1,
NP_001372283.1,
NP_001372290.1,
NP_001350458.1,
NP_001372282.1,
NP_001372285.1,
NP_057202.4,
XP_024302566.1
|
| Others |
UniRef100:
UniRef100_H3BM14,
UniRef100_Q9Y5A7
UniRef90:
UniRef90_Q9Y5A7
UniRef50:
UniRef50_Q9Y5A7
UniGene:
Hs.647082
CCDS:
CCDS87565.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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