| Type | Description |
|---|---|
| Definition | zinc finger RNA binding protein |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 11:19:00 | overexpression of ZFR in CRC and liver cancer cells led to accelerated tumor development. Consistently, knockdown of ZFR resulted in significantly decelerated tumor development. | 31010678 |
| 2020-04-11 11:27:00 | Hyperglycaemia elevates ZFR in vivo and in vitro. ZFR can promote the proliferation and migration of human retinal microvascular endothelial cells cultured in high glucose condition. | 30914198 |
| 2019-11-09 11:53:00 | ZFR was confirmed as a target gene of miR-141-3p and negatively correlated with miR-141-3p expression in non-small cell lung cancer tissues. | 30611568 |
| 2018-12-22 10:28:00 | ZFR expression is tightly controlled during macrophage development; monocytes express truncated ZFR isoforms, while macrophages induce full-length ZFR to modulate macrophage-specific alternative splicing. | 29559679 |
| 2018-12-01 10:07:00 | Identified a new circRNA, circZFR, that was significantly upregulated in papillary thyroid carcinoma (PTC). CircZFR could promote C8orf4 expression via serving as a competing endogenous RNA of miR-1261 in PTC cells. Rescue assays indicated that restoration of C8orf4 significantly attenuated the inhibitory effects of circZFR knockdown on PTC cell proliferation, migration and invasion. | 29842886 |
| Type | IDs |
|---|---|
| Synonymous | SPG71, ZFR1 |
| Gene |
UniProtKB-ID:
ZFR_HUMAN,
Q05D65_HUMAN
UniprotKB:
Q96KR1,
Q05D65
UniParc:
UPI0000D4972C,
UPI00001BBB38
EMBL:
AF100742,
BC062986,
AK025481,
BC107417,
AL137258,
BC051893,
BC017879,
AC008949,
BC137084,
BC030540,
AJ314790
Ensembl:
ENSG00000056097
KO:
hsa:51663
|
| Nucleutide sequences |
EMBL-CDS:
CAC40818.1,
BAB15147.1,
CAB70659.1,
AAI07418.1,
AAD40385.1,
AAH30540.1,
AAH51893.1,
AAH62986.1,
AAI37085.1,
AAH17879.1
Ensembl_TRS:
ENST00000265069
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265069
RefSeq:
NP_057191.2
|
| Others |
UniRef100:
UniRef100_Q96KR1,
UniRef100_Q05D65
UniRef90:
UniRef90_Q96KR1,
UniRef90_Q05D65
UniRef50:
UniRef50_O88532,
UniRef50_Q05D65
UniGene:
Hs.435231
CCDS:
CCDS34139.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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