| Type | Description |
|---|---|
| Definition | GINS complex subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:30:00 | Knockdown of GINS2 inhibits proliferation and promotes apoptosis through the p53/GADD45A pathway in non-small-cell lung cancer. | 32181475 |
| 2021-03-13 13:14:00 | GINS2 facilitates epithelial-to-mesenchymal transition in non-small-cell lung cancer through modulating PI3K/Akt and MEK/ERK signaling. | 31681988 |
| 2020-05-02 10:49:00 | GINS2 is closely related to the occurrence and development of glioma, and is likely to become a prognostic marker for glioma patients, as well as a potential therapeutic target in the treatment of glioma | 30338650 |
| 2020-04-04 11:57:00 | GINS2 plays an important role in cell proliferation and apoptosis of thyroid cancer by regulating the expressions of CITED2 and LOXL2, which may be a potential biomarker for diagnosis or prognosis and a drug target for therapy. | 30177819 |
| 2019-08-03 10:20:00 | mRNA expressions of all GINS subunits were significantly up-regulated in hepatocellular carcinoma tumor than in non-tumor liver tissues. | 30413605 |
| Type | IDs |
|---|---|
| Synonymous | HSPC037, PSF2, Pfs2 |
| Gene |
UniProtKB-ID:
PSF2_HUMAN
UniprotKB:
Q9Y248
UniParc:
UPI000006D930
EMBL:
AK001275,
BC003186,
BC062444,
BC010164,
AF151880,
AF125098,
AF201939,
CH471114,
CR457186
Ensembl:
ENSG00000131153
KO:
hsa:51659
|
| Nucleutide sequences |
EMBL-CDS:
BAA91595.1,
AAH62444.1,
EAW95444.1,
AAD39915.1,
AAH03186.1,
CAG33467.1,
EAW95443.1,
AAD34117.1,
AAH10164.1,
AAF86875.1
Gene_ORFName:
CGI-122,
DC5,
HSPC037
Ensembl_TRS:
ENST00000253462
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000253462
RefSeq:
NP_057179.1
|
| Others |
UniRef100:
UniRef100_Q9Y248
UniRef90:
UniRef90_Q9Y248
UniRef50:
UniRef50_Q9Y248
UniGene:
Hs.433180
CCDS:
CCDS10953.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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