| Type | Description |
|---|---|
| Definition | serine/threonine/tyrosine interacting like 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:30:00 | STYXL1 promotes malignant progression of hepatocellular carcinoma via downregulating CELF2 through the PI3K/Akt pathway. | 32271415 |
| 2020-07-04 12:35:00 | Silencing serine/threonine/tyrosine-interacting-like protein 1 (STYXL1) inhibited glioma cell growth, soft agar colony formation, migration, invasion, proliferation, and xenograft tumor growth [Review]. | 31146910 |
| 2020-02-08 11:33:00 | We have detected this variant via whole exome sequencing in a homozygous state in two families. Segregation analyses in our families and thorough validation in international genetic databases provides evidence that this variant is most likely benign. This is important information for genetic counselling. The role of STYXL1 variants in human disease needs to be established | 30472486 |
| 2019-07-20 11:16:00 | These findings show that MK-STYX decreases the number of HDAC6-containing aggregates and alters their localization, sustains microtubule acetylation, and increases detyrosination of microtubules, implicating MK-STYX as a signaling molecule in HDAC6 activity. | 30909412 |
| 2016-01-30 12:02:00 | this study revealed STYXL1 as a novel candidate gene for moderate intellectual disability, seizures and behavioral complexities. | 25724587 |
| Type | IDs |
|---|---|
| Synonymous | DUSP24, MK-STYX, MKSTYX |
| Gene |
UniProtKB-ID:
STYL1_HUMAN,
A0A024R4L1_HUMAN,
Q7Z3H6_HUMAN
UniprotKB:
Q9Y6J8,
A0A024R4L1,
Q7Z3H6
UniParc:
UPI00001A9D11,
UPI000002AE66,
UPI000002AE68,
UPI000002AE65,
UPI000012F694,
UPI000002AE67
EMBL:
AF188201,
AF188202,
AF188203,
AF069762,
AF169647,
BC024035,
AC006330,
AF169648,
CH471220,
BX537896,
AF188204
Ensembl:
ENSG00000127952
KO:
hsa:51657
|
| Nucleutide sequences |
EMBL-CDS:
AAF04113.1,
AAF04111.1,
AAD53724.1,
AAF04114.1,
AAD36983.1,
AAS07535.1,
AAD53723.1,
AAH24035.1,
AAF04112.1,
EAW71793.1,
EAW71794.1,
EAW71791.1,
EAW71792.1,
CAD97887.1
Gene_ORFName:
hCG_41355
Ensembl_TRS:
ENST00000431581,
ENST00000248600,
ENST00000340062,
ENST00000359697,
ENST00000360591
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000392221,
ENSP00000353798,
ENSP00000248600,
ENSP00000352726,
ENSP00000343383
RefSeq:
XP_016867789.1,
NP_057170.1,
XP_016867790.1,
NP_001304716.1,
NP_001304715.1,
XP_011514595.1,
NP_001304714.1,
XP_011514594.1,
XP_016867788.1,
XP_016867787.1,
XP_011514602.1,
XP_016867791.1,
NP_001304718.1,
XP_016867785.1,
NP_001304717.1,
XP_016867786.1
|
| Others |
UniRef100:
UniRef100_Q9Y6J8,
UniRef100_Q7Z3H6
UniRef90:
UniRef90_Q9Y6J8,
UniRef90_Q9Y6J8-4
UniRef50:
UniRef50_Q9Y6J8,
UniRef50_Q9Y6J8-4
UniGene:
Hs.11615
CCDS:
CCDS83193.1,
CCDS5580.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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