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5165 PDK3

5165

PDK3

pyruvate dehydrogenase kinase 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition pyruvate dehydrogenase kinase 3

研究结论

Date Results Publications
2020-12-12 13:28:00 Energy metabolism and mitochondrial defects in X-linked Charcot-Marie-Tooth (CMTX6) iPSC-derived motor neurons with the p.R158H PDK3 mutation. 32504000
2020-11-28 13:15:00 Effect of pH on the structure and function of pyruvate dehydrogenase kinase 3: Combined spectroscopic and MD simulation studies. 31982536
2020-09-19 16:24:00 miR-497-5p inhibits gastric cancer cell proliferation and growth through targeting PDK3. 31409724
2020-06-20 12:12:00 PDK3 forms a positive feedback loop with HSF1 to drive glycolysis in chemoresistance. 31244938
2017-11-18 10:56:00 The pyruvate dehydrogenase kinases (PDKs) PDK1 and PDK3 are direct targets of KDM4A and E2F1 and modulate the switch between glycolytic metabolism and mitochondrial oxidation. 27626669

名称对应

Type IDs
Synonymous CMTX6, GS1-358P8.4
Gene
UniProtKB-ID: PDK3_HUMAN
UniprotKB: Q15120
UniParc: UPI00002124D4, UPI00001314C5
EMBL: L42452, AK301965, CH471074, BC015948
Ensembl: ENSG00000067992
KO: hsa:5165
Nucleutide sequences
EMBL-CDS: AAH15948.1, BAG63378.1, AAC42011.1, EAW99019.1
Ensembl_TRS: ENST00000568479, ENST00000648777, ENST00000379162
Protein sequencees
Ensembl_PRO: ENSP00000497727, ENSP00000368460, ENSP00000498864
RefSeq: NP_001135858.1, NP_005382.1
Others
UniRef100: UniRef100_Q15120
UniRef90: UniRef90_Q15120
UniRef50: UniRef50_Q15120
UniGene: Hs.296031
CCDS: CCDS14212.1, CCDS48088.1

全选

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研究热度

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