| Type | Description |
|---|---|
| Definition | dehydrogenase/reductase 7 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 11:35:00 | Single nucleotide polymorphism in DHRS7 gene is associated with smoking in African americans. | 29216386 |
| 2018-07-07 10:19:00 | identification of new substrates of human DHRS7 | 28687384 |
| 2017-07-22 11:38:00 | Data suggest that (1) cortisone is a substrate of DHRS7 and is reduced to 20beta-dihydrocortisone, (2) androstenedione is not a relevant substrate of DHRS7, (3) DHRS7 catalyzes the oxidoreduction of 5alpha-dihydrotestosterone to 3alpha-androstanediol with a suppressive effect on androgen receptor transcriptional activity, and (4) DHRS7 is anchored in endoplasmic reticulum membrane with cytoplasmic orientation. | 28457967 |
| 2016-05-07 11:08:00 | DHRS7 participates in the reductive metabolism of steroids and retinoids.Expression patterns of DHRS7 at the mRNA as well as protein level were determined in a panel of various human tissue samples. | 26466768 |
| 2014-10-11 12:50:00 | DHRS7 containing TEV-cleavable His10 and FLAG-tag was cloned and expressed in the Sf9 cell line. | 24316191 |
| Type | IDs |
|---|---|
| Synonymous | CGI-86, SDR34C1, retDSR4, retSDR4 |
| Gene |
UniProtKB-ID:
DHRS7_HUMAN
UniprotKB:
Q9Y394
UniParc:
UPI000006F3A8,
UPI000004C78C
EMBL:
AF126782,
BC000637,
AF151844,
AY359031,
BC007337,
CH471061,
AL163853,
AK313285
Ensembl:
ENSG00000100612
KO:
hsa:51635
|
| Nucleutide sequences |
EMBL-CDS:
BAG36093.1,
AAD34081.1,
AAH07337.1,
AAQ89390.1,
AAF06941.1,
EAW80770.1,
AAH00637.1
Gene_ORFName:
CGI-86,
UNQ285/PRO3448
Ensembl_TRS:
ENST00000557185,
ENST00000216500,
ENST00000536410
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000442993,
ENSP00000216500,
ENSP00000451882
RefSeq:
NP_001309210.1,
NP_057113.1,
XP_016876857.1,
NP_001309211.1,
NP_001309209.1
|
| Others |
UniRef100:
UniRef100_Q9Y394
UniRef90:
UniRef90_Q9Y394
UniRef50:
UniRef50_Q9Y394
UniGene:
Hs.59719
CCDS:
CCDS81810.1,
CCDS9743.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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