| Type | Description |
|---|---|
| Definition | OTU domain containing 6B |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:20:00 | DUB-independent regulation of pVHL by OTUD6B suppresses hepatocellular carcinoma. | 32323143 |
| 2020-10-03 12:55:00 | OTUD6B-AS1 Might Be a Novel Regulator of Apoptosis in Systemic Sclerosis. | 31156645 |
| 2017-10-21 12:21:00 | The global OTUD6B expression level does not change significantly between nonneoplastic and malignant tissues, suggesting that modifications of splicing factors during the process of transformation are responsible for this isoform switch. | 27864334 |
| 2017-04-29 10:13:00 | OTUD6B encodes a deubiquitinating enzyme; study reports biallelic pathogenic variants in OTUD6B in 12 individuals from 6 families with intellectual disability syndrome associated with seizures & dysmorphic features; other features include developmental delay, microcephaly, absent speech, hypotonia, growth retardation, feeding difficulties, structural brain abnormalities, malformations of heart & musculoskeleton. | 28343629 |
| 2011-08-06 11:12:00 | down-regulation of Otud-6b expression after prolonged cytokine stimulation may be required for cell proliferation in B lymphocytes | 21267069 |
| Type | IDs |
|---|---|
| Synonymous | CGI-77, DUBA-5, DUBA5, IDDFSDA |
| Gene |
UniProtKB-ID:
OTU6B_HUMAN,
A0A087X0W9_HUMAN
UniprotKB:
Q8N6M0,
A0A087X0W9
UniParc:
UPI0000E5AF0F,
UPI000057A097,
UPI00000706A8
EMBL:
AL137441,
AK291646,
BC029760,
AF151836,
AC087439,
CH471060,
AK293843
Ensembl:
ENSG00000155100
KO:
hsa:51633
|
| Nucleutide sequences |
EMBL-CDS:
BAG57241.1,
AAD34073.1,
BAF84335.1,
AAH29760.1,
CAB70738.1,
EAW91676.1
Gene_ORFName:
CGI-77,
hCG_32310
Ensembl_TRS:
ENST00000615618,
ENST00000404789,
ENST00000285420,
ENST00000617869
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000384190,
ENSP00000481196,
ENSP00000483706,
ENSP00000285420
RefSeq:
XP_011515431.2,
NP_001273674.1,
NP_057107.4
|
| Others |
UniRef100:
UniRef100_Q8N6M0
UniRef90:
UniRef90_Q8N6M0
UniRef50:
UniRef50_Q8N6M0
UniGene:
Hs.30532
CCDS:
CCDS6253.2,
CCDS69513.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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