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51621 KLF13

51621

KLF13

Kruppel like factor 13

protein-coding

Homo sapiens

基因描述

Type Description
Definition Kruppel like factor 13

研究结论

Date Results Publications
2020-07-18 12:23:00 Our results show that the S156N and P163S variants may affect the transcriptional function of KLF13 and physical interaction with TBX5. These results identified KLF13 as a potential genetic risk factor for congenital heart disease. 32293321
2018-12-01 12:14:00 Results show that cg07814318 methylation in blood was significantly associated with obesity and correlated with several obesity-related physical and biochemical traits. The exome sequencing of KLF13 gene in blood identified nine SNPs within its gene body, and two SNPs as cis-meQTL of cg07814318. The sequencing variations within KLF13 genes could drive dynamic modifications of obesity-related CpG methylation. 28508896
2018-10-20 12:13:00 KLF13 functions as a tumor suppressor protein in PCa, and the pharmacological activation of KLF13 might represent a potential approach for the treatment of prostate cancer. 29843216
2018-05-05 10:10:00 Our results suggest the cg07814318 site could be involved in orexigenic processes, and also implicate KLF13 in obesity. Our findings are the first to associate methylation levels in blood with brain activity in obesity-related regions, and further support previous findings between ghrelin, brain activity and genetic differences. 28194012
2018-04-14 11:51:00 SLC44A1 and KLF13 may be involved in tumorigenesis and the metastasis of colon cancer by miRNA regulation 29408621

名称对应

Type IDs
Synonymous BTEB3, FKLF2, NSLP1, RFLAT-1, RFLAT1
Gene
UniProtKB-ID: KLF13_HUMAN, X5DNR2_HUMAN
UniprotKB: Q9Y2Y9, X5DNR2
UniParc: UPI000012DEDC
EMBL: BC010438, AF150628, CH471216, BC012741, AF132599, BC013946, KJ534876
Ensembl: ENSG00000169926, ENSG00000275746
KO: hsa:51621
Nucleutide sequences
EMBL-CDS: AAH10438.1, AAD26864.1, AAH12741.1, AAD34020.1, AAH13946.1, EAW61265.1, AHW56516.1
Gene_ORFName: hCG_38887
Ensembl_TRS: ENST00000621843, ENST00000307145
Protein sequencees
Ensembl_PRO: ENSP00000302456, ENSP00000484904
RefSeq: NP_001289390.1, NP_057079.2
Others
UniRef100: UniRef100_Q9Y2Y9
UniRef90: UniRef90_Q9Y2Y9
UniRef50: UniRef50_Q9Y2Y9
UniGene: Hs.525752
CCDS: CCDS10025.1

全选

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