UBE2D4 - ubiquitin conjugating enzyme E2 D4 (putative)-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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51619 UBE2D4

基因描述

Type	Description
Definition	ubiquitin conjugating enzyme E2 D4 (putative)

研究结论

Date	Results	Publications
2016-12-24 10:48:00	Knockdown of UBE2D4 caused an increase in p53 protein levels, and knockdown of p53 attenuated not only cadmium-induced apoptosis, but also cadmium-induced apoptosis-related gene expression.	26912277

名称对应

Type	IDs
Synonymous	HBUCE1
Gene	UniProtKB-ID: UB2D4_HUMAN, A0A024RA90_HUMAN, Q9UQL0_HUMAN UniprotKB: Q9Y2X8, A0A024RA90, Q9UQL0 UniParc: UPI000007403F, UPI0000070235 EMBL: AK001446, AF125044, BC004104, CH236951, AF125045, CH471073 Ensembl: ENSG00000078967 KO: hsa:51619
Nucleutide sequences	EMBL-CDS: EAL24010.1, AAD31180.1, EAW94182.1, AAH04104.1, BAA91697.1, EAW94184.1, EAW94183.1, AAD31181.1 Gene_ORFName: hCG_17272, hCG_17272 Ensembl_TRS: ENST00000222402
Protein sequencees	Ensembl_PRO: ENSP00000222402 RefSeq: XP_016867783.1, XP_011513722.1, XP_024302564.1, XP_016867784.1, XP_016867781.1, XP_006715797.1, XP_016867782.1, XP_011513725.1, XP_024302563.1, NP_057067.1, XP_011513724.1
Others	UniRef100: UniRef100_Q9UQL0, UniRef100_Q9Y2X8 UniRef90: UniRef90_A0A286Y4T4, UniRef90_Q9Y2X8 UniRef50: UniRef50_Q9Y2X8, UniRef50_A0A286Y4T4 UniGene: Hs.19196 CCDS: CCDS5474.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
32814053	Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. Cell Rep Christian Haenig , Nir Atias , Alexander K Taylor , Arnon Mazza , Martin H Schaefer , Jenny Russ , Sean-Patrick Riechers , Shushant Jain , Maura Coughlin , Jean-Fred Fontaine , Brian D Freibaum , Lydia Brusendorf , Martina Zenkner , Pablo Porras , Martin Stroedicke , Sigrid Schnoegl , Kristin Arnsburg , Annett Boeddrich , Lucia Pigazzini , Peter Heutink , J Paul Taylor , Janine Kirstein , Miguel A Andrade-Navarro , Roded Sharan , Erich E Wanker	2020-08-18	-
32296183	A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G CotÃ© , Meaghan Daley , Steven Deimling , Alice Desbuleux , AmÃ©lie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , IstvÃ¡n A KovÃ¡cs , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood	2020-04-01	-
31515488	Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations. Nat Commun Robert Fragoza , Jishnu Das , Shayne D Wierbowski , Jin Liang , Tina N Tran , Siqi Liang , Juan F Beltran , Christen A Rivera-Erick , Kaixiong Ye , Ting-Yi Wang , Li Yao , Matthew Mort , Peter D Stenson , David N Cooper , Xiaomu Wei , Alon Keinan , John C Schimenti , Andrew G Clark , Haiyuan Yu	2019-09-12	-
31087003	Mechanism and chain specificity of RNF216/TRIAD3, the ubiquitin ligase mutated in Gordon Holmes syndrome. Hum. Mol. Genet. Ramkumar Seenivasan , Thomas Hermanns , Tamara Blyszcz , Michael Lammers , Gerrit J K Praefcke , Kay Hofmann	2019-09-01	-
30884854	Analysis of the Zn-Binding Domains of TRIM32, the E3 Ubiquitin Ligase Mutated in Limb Girdle Muscular Dystrophy 2H. Cells Elisa Lazzari , Medhat S El-Halawany , Matteo De March , Floriana Valentino , Francesco Cantatore , Chiara Migliore , Silvia Onesti , Germana Meroni	2019-03-16	-
30017913	The MALDI-TOF E2/E3 Ligase Assay as Universal Tool for Drug Discovery in the Ubiquitin Pathway. Cell Chem Biol Virginia De Cesare , Clare Johnson , Victoria Barlow , James Hastie , Axel Knebel , Matthias Trost	2018-09-20	-
30097011	Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay. BMC Biol. Joanna Koszela , Nhan T Pham , David Evans , Stefan Mann , Irene Perez-Pi , Steven Shave , Derek F J Ceccarelli , Frank Sicheri , Mike Tyers , Manfred Auer	2018-08-10	-
29323787	Inhibition of UVSSA ubiquitination suppresses transcription-coupled nucleotide excision repair deficiency caused by dissociation from USP7. FEBS J. Mitsuru Higa , Kiyoji Tanaka , Masafumi Saijo	2018-03-01	-
28757353	Osmotic and heat stress-dependent regulation of MLK4Î² and MLK3 by the CHIP E3 ligase in ovarian cancer cells. Cell. Signal. Natalya A Blessing , Srimathi Kasturirangan , Evan M Zink , April L Schroyer , Deborah N Chadee	2017-11-01	-
28986522	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism. Nat Commun Giulia Antoniali , Fabrizio Serra , Lisa Lirussi , Mikiei Tanaka , Chiara D'Ambrosio , Shiheng Zhang , Slobodanka Radovic , Emiliano Dalla , Yari Ciani , Andrea Scaloni , Mengxia Li , Silvano Piazza , Gianluca Tell	2017-10-06	-

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