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51608 GET4

51608

GET4

golgi to ER traffic protein 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition golgi to ER traffic protein 4

研究结论

Date Results Publications
2015-04-25 10:25:00 Both TRC35 and Ubl4A have distinct C-terminal binding sites on Bag6 defining a minimal Bag6 complex. 25535373
2014-07-19 11:50:00 The crystal structure of the Get3-Get4-Get5 complex in an ATP-bound state is presented. 24727835
2013-09-28 11:20:00 Data indicate that BCL2-associated athanogene 6 (BAG6) appears to be the central component for the process, as depletion of BAG6 leads to the loss of both UBL4A and GET4 proteins and resistance to cell killing by DNA-damaging agents. 23723067
2013-09-07 11:45:00 Data indicate that the Bag6-Ubl4A-Trc35 complex is localized to the endoplasmic reticulum (ER) membrane to regulate ER-associated degradation (ERAD). 23665563
2013-06-08 12:54:00 SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation. 23246001

名称对应

Type IDs
Synonymous C7orf20, CEE, CGI-20, TRC35
Gene
UniProtKB-ID: GET4_HUMAN
UniprotKB: Q7L5D6
UniParc: UPI0000073D69, UPI00001AE543
EMBL: CH236965, AK097899, BC003550, AK125863, AF132954, AK024305, AL133014
Ensembl: ENSG00000239857
KO: hsa:51608
Nucleutide sequences
EMBL-CDS: CAB61355.1, BAG51289.1, BAG53546.1, AAD27729.1, AAH03550.2, BAG54258.1, EAL23708.1
Gene_ORFName: CGI-20
Ensembl_TRS: ENST00000265857, ENST00000407192
Protein sequencees
Ensembl_PRO: ENSP00000265857, ENSP00000385646
RefSeq: NP_057033.2
Others
UniRef100: UniRef100_Q7L5D6
UniRef90: UniRef90_Q7L5D6
UniRef50: UniRef50_Q7L5D6
UniGene: Hs.107387
CCDS: CCDS5317.1

全选

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