| Type | Description |
|---|---|
| Definition | pyruvate dehydrogenase E1 alpha 1 subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:20:00 | Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis. | 33022274 |
| 2019-12-21 12:20:00 | LDHA/PDHA1 changes in Head and Neck Squamous Cell Carcinoma (HNSCC) resulted in a broad metabolic reprogramming while intracellular molecules including polyunsaturated fatty acids and nitrogen metabolism related metabolites underlie the malignant changes. | 31100640 |
| 2019-11-09 11:25:00 | PGC1alpha reversed the Warburg effect by upregulating the expression of pyruvate dehydrogenase E1 alpha 1 subunit and mitochondrial pyruvate carrier 1 to increase pyruvate flux into the mitochondria for oxidation, whereas simultaneously promoting mitochondrial biogenesis and fusion to mediate the metabolic switch to oxidative phosphorylation. | 29700317 |
| 2019-10-07 10:05:00 | We demonstrate here that silencing of PDHA1 expression prevents proliferation of HUVECs and inhibits angiogenesis in vitro as well as in vivo | 31471554 |
| 2019-08-10 11:42:00 | insulin-mediated p-PDHA1 is involved in the regulation of HepG2 cell proliferation through RhoA signaling pathway. | 30226812 |
| Type | IDs |
|---|---|
| Synonymous | PDHA, PDHAD, PDHCE1A, PHE1A |
| Gene |
UniProtKB-ID:
ODPA_HUMAN,
A0A024RBX9_HUMAN
UniprotKB:
P08559,
A0A024RBX9
UniParc:
UPI0001914B35,
UPI0001914BAA,
UPI0000D4E0D1,
UPI0000130C10
EMBL:
AF125084,
AF125065,
AF125088,
EF590117,
AK222740,
AK296341,
AF125070,
D90084,
J03575,
M29164,
AF125063,
AF125055,
AF125057,
AF125074,
AF125069,
AF125053,
AK312263,
AF125078,
X52709,
AF125068,
AF125085,
AF125066,
AF125081,
AF125076,
M29156,
AF125072,
AK296457,
AF125061,
BC002406,
M29158,
M29155,
M29163,
M29160,
AF125054,
AF125060,
L13318,
J03503,
M29162,
AF125086,
M29157,
AF125082,
M29161,
AF125087,
AF125071,
AF125059,
AF125079,
AL732326,
X52710,
AF125075,
CH471074,
AF125083,
AF125064,
M27257,
AF125073,
L48690,
AK293250,
M24848,
AF125080,
AF125056,
AF125062,
M29159,
AF125067,
AF125058
Ensembl:
ENSG00000131828
KO:
hsa:5160
|
| Nucleutide sequences |
EMBL-CDS:
AAD23864.1,
AAA36533.1,
AAB59581.1,
AAD23852.1,
AAA60051.1,
AAD23842.1,
AAD23854.1,
AAD23853.1,
AAD23848.1,
BAH11476.1,
AAD23868.1,
BAA14121.1,
AAD23849.1,
AAH02406.1,
AAD23863.1,
AAA60227.1,
AAD23841.1,
BAD96460.1,
AAD23867.1,
AAA60055.1,
AAD23845.1,
AAA60050.1,
AAD23875.1,
AAD23860.1,
AAD23846.1,
AAD23857.1,
BAG35194.1,
AAD23855.1,
AAD23866.1,
CAA36934.1,
AAD23859.1,
AAD23843.1,
EAW98960.1,
AAD23858.1,
AAD23851.1,
AAD23850.1,
AAD23856.1,
AAD23872.1,
AAD23847.1,
AAD23869.1,
BAH12361.1,
AAD23876.1,
AAD23871.1,
AAD23874.1,
AAD23873.1,
AAD23844.1,
AAD23861.1,
AAD23870.1,
AAD23862.1,
ABQ59099.1,
CAA36933.1,
BAH12323.1,
EAW98961.1
Gene_ORFName:
hCG_17571
Ensembl_TRS:
ENST00000379806,
ENST00000545074,
ENST00000540249,
ENST00000422285
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000440761,
ENSP00000369134,
ENSP00000394382,
ENSP00000438550
RefSeq:
NP_001166927.1,
NP_001166925.1,
NP_001166926.1,
NP_000275.1,
XP_016885063.1
|
| Others |
UniRef100:
UniRef100_P08559
UniRef90:
UniRef90_P08559
UniRef50:
UniRef50_P08559
UniGene:
Hs.530331
CCDS:
CCDS55382.1,
CCDS14192.1,
CCDS55381.1,
CCDS55380.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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