| Type | Description |
|---|---|
| Definition | tyrosyl-DNA phosphodiesterase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:36:00 | Untangling trapped topoisomerases with tyrosyl-DNA phosphodiesterases. | 32653827 |
| 2021-03-13 13:19:00 | Tyrosyl-DNA phosphodiesterase 2 (TDP2) repairs topoisomerase 1 DNA-protein crosslinks and 3'-blocking lesions in the absence of tyrosyl-DNA phosphodiesterase 1 (TDP1). | 32460231 |
| 2021-02-20 13:28:00 | Effects of TDP2/VPg Unlinkase Activity on Picornavirus Infections Downstream of Virus Translation. | 32023921 |
| 2020-11-21 13:21:00 | TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands. | 32277721 |
| 2020-09-12 16:05:00 | Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2. | 32356875 |
| Type | IDs |
|---|---|
| Synonymous | AD022, EAP2, EAPII, TTRAP, dJ30M3.3, hTDP2 |
| Gene |
UniProtKB-ID:
TYDP2_HUMAN,
A0A384MDM5_HUMAN
UniprotKB:
O95551,
A0A384MDM5
UniParc:
UPI00001584B7,
UPI0001BE80DC,
UPI0000032018
EMBL:
BC110375,
AL031775,
GQ891344,
AK296623,
AF201687,
AF223469,
AK298699,
AJ269473,
AK002168,
AY613922,
BC017553
Ensembl:
ENSG00000111802
KO:
hsa:51567
|
| Nucleutide sequences |
EMBL-CDS:
AAF64144.1,
BAA92119.1,
BAG60857.1,
BAG59230.1,
CAB92966.1,
AAT09764.1,
AAG35600.1,
AAH17553.1,
AAI10376.1,
ADO22206.1
Gene_ORFName:
AD-022
Ensembl_TRS:
ENST00000378198
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000367440
RefSeq:
NP_057698.2
|
| Others |
UniRef100:
UniRef100_O95551
UniRef90:
UniRef90_O95551
UniRef50:
UniRef50_O95551
UniGene:
Hs.403010
CCDS:
CCDS4557.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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