| Type | Description |
|---|---|
| Definition | cyclin dependent kinase 2 interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2019-04-27 10:45:00 | Silencing CINP had the most potent inhibitory effect on cell growth in KLF5-expressing cells but did not affect parental TSU-Pr1 cells. Further analyses not only confirmed the physical interaction between KLF5 and CINP, also demonstrated that knockdown of CINP attenuated the effects of KLF5 on cell cycle progression, apoptosis and tumorigenesis. | 30289973 |
| 2011-10-01 12:07:00 | NS5B delays cells in S phase through interaction with CINP and relocalization of the protein from the nucleus to the cytoplasm | 21628470 |
| 2010-01-21 00:00:00 | CINP is part of the Cdc7-dependent mechanism of origin firing and a functional and physical link between Cdk2 and Cdc7 complexes at the origins | 16082200 |
| 2010-01-21 00:00:00 | CINP interacts with ATR-interacting protein and regulates ATR-dependent signaling, resistance to replication stress, and G2 checkpoint integrity. | 19889979 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CINP_HUMAN,
A0A024R6M9_HUMAN
UniprotKB:
Q9BW66,
A0A024R6M9
UniParc:
UPI0001D0C47F,
UPI0001D0C47E,
UPI0000049CD5
EMBL:
CH471061,
AF228149,
AK056112,
BU174070,
DA167716,
AL137229,
BC000600,
CR457178,
AF228148
Ensembl:
ENSG00000100865
KO:
hsa:51550
|
| Nucleutide sequences |
EMBL-CDS:
BAB71095.1,
AAF44747.1,
AAH00600.1,
AAF44748.1,
CAG33459.1,
EAW81785.1,
EAW81786.1
Gene_ORFName:
hCG_24751
Ensembl_TRS:
ENST00000541568,
ENST00000536961,
ENST00000559514,
ENST00000216756
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000453839,
ENSP00000216756,
ENSP00000442377,
ENSP00000442057
RefSeq:
NP_001306975.1,
NP_116019.1
|
| Others |
UniRef100:
UniRef100_Q9BW66
UniRef90:
UniRef90_Q9BW66
UniRef50:
UniRef50_Q9BW66
UniGene:
Hs.129634
CCDS:
CCDS9972.1,
CCDS53915.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31515488 |
Nat Commun Robert Fragoza , Jishnu Das , Shayne D Wierbowski , Jin Liang , Tina N Tran , Siqi Liang , Juan F Beltran , Christen A Rivera-Erick , Kaixiong Ye , Ting-Yi Wang , Li Yao , Matthew Mort , Peter D Stenson , David N Cooper , Xiaomu Wei , Alon Keinan , John C Schimenti , Andrew G Clark , Haiyuan Yu |
2019-09-12 | - |
| 30289973 |
Int. J. Cancer Qiao Wu , Changying Fu , Menglin Li , Juan Li , Zhigui Li , Leilei Qi , Xinpei Ci , Gui Ma , Ang Gao , Xing Fu , Jun A , Na An , Mingcheng Liu , Yixiang Li , Jamie L King , Liya Fu , Baotong Zhang , Jin-Tang Dong |
2019-02-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26472760 |
Gene essentiality and synthetic lethality in haploid human cells. Science Vincent A Blomen , Peter Májek , Lucas T Jae , Johannes W Bigenzahn , Joppe Nieuwenhuis , Jacqueline Staring , Roberto Sacco , Ferdy R van Diemen , Nadine Olk , Alexey Stukalov , Caleb Marceau , Hans Janssen , Jan E Carette , Keiryn L Bennett , Jacques Colinge , Giulio Superti-Furga , Thijn R Brummelkamp |
2015-11-27 | - |
| 26354767 |
Genetics Melanie L Bailey , Tejomayee Singh , Patricia Mero , Jason Moffat , Philip Hieter |
2015-11-01 |
LINC00173,
TUBA1B,
CDR2,
DLC1,
SPAG11B,
UBAC1,
SLC35A1,
COPS6,
DIDO1,
EFHC1,
TBCB,
MTFMT,
ZC3H18,
COL1A2,
COL12A1,
DNAJC21,
LETM2,
RALYL,
ZNF563,
B3GALNT2,
CYBB,
CYLD,
TMEM65,
AP2A1,
SPRED1,
MMAA,
EPOR,
FANCD2,
C6orf136,
RSBN1L,
FGA,
PUF60,
TXLNGY,
EBF3,
GAK,
TRIM58,
NECTIN3,
FAM32A,
RBMX,
GMDS,
OR51V1,
CDH19,
C5orf51,
C5orf64,
GRIK3,
GRM3,
CPSF1,
EIF4E3,
LRRTM1,
LCE1B,
ITGAV,
GAMTP1,
HERC2P2,
LPA,
MEP1A,
MOCS1,
NUDT4P1,
PALM2-AKAP2,
NDUFB9,
RERE,
TRAT1,
PHF20L1,
CDK18,
NAT8B,
CINP,
ZFR,
RAB4B,
POLR2K,
EXOSC4,
SPDL1,
SRBD1,
RFWD3,
FBXW7,
TNFRSF19,
H2AFY2,
RNPC3,
TMEM126B,
C8orf44,
PRPSAP1,
C5orf15,
PTGDS,
SENP7,
SHROOM4,
PTPRN2,
RAG1,
VPS16,
SLC17A1,
SNRNP70,
SNRPB2,
SNRPF,
SPTBN1,
SSBP1,
SUPT6H,
MED22,
BUB1B,
OSGIN2,
MPPED1,
GGCT,
NELFE
|
| 26050649 |
BAALC potentiates oncogenic ERK pathway through interactions with MEKK1 and KLF4. Leukemia K Morita , Y Masamoto , K Kataoka , J Koya , Y Kagoya , H Yashiroda , T Sato , S Murata , M Kurokawa |
2015-11-01 |
MAP3K1,
BAALC,
KLF4
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 26673895 |
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife Koray Kırlı , Samir Karaca , Heinz Jürgen Dehne , Matthias Samwer , Kuan Ting Pan , Christof Lenz , Henning Urlaub , Dirk Görlich |
2015-01-01 |
CHA1,
KRR1,
SRO9,
STE50,
RRP7,
RNQ1,
DCC1,
GBP2,
SAT4,
RVS161,
YCR016W,
PWP2,
SSK22,
SOL2,
PAT1,
YCR087C-A,
OCA4,
MOB2,
EPL1,
BUD27,
FRS2,
LOC1,
YFR016C,
LSB3,
RPL2A,
PHO4,
SAP155,
IRC6,
ENT4,
PRP19,
RIX7,
YLL032C,
FRA1,
ISA1,
SPA2,
PUF3,
RPL8B,
NOC3,
SSL1,
SSK1,
NSE1,
RLP24,
SDO1,
ADE16,
RPL15A,
STU2,
RPS0B,
FRS1,
BMT6,
KIN2,
HRT3,
REX3,
YLR108C,
CFT2,
MSL5,
ACE2,
STM1,
YLR157C-A,
APS1,
CBF5,
SWI6,
SKG3,
HCR1,
PWP1,
NOP56,
BUR2,
GPN3,
DBP9,
GCD7,
SGD1,
STE11,
NMD4,
RPS22B,
ROM2,
STP3,
IKI3,
REH1,
AFG2,
UTP21,
ATG17,
TUS1,
MAG2,
ATG23,
RPS1A,
FPR4,
PDP3,
CDC24,
RBG1,
FUN12,
MTW1,
PRP45,
MAK16,
ECM1,
GPB2,
VPS8,
KIN3,
CDC15,
YAT1,
WHI4
|
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员