| Type | Description |
|---|---|
| Definition | periphilin 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:28:00 | Periphilin self-association underpins epigenetic silencing by the HUSH complex. | 32976585 |
| 2017-01-14 11:56:00 | The haploid screen identified HUSH, an epigenetic heterochromatin repressor complex composed of three subunits, TASOR, MPP8 and Periphilin. (Review) | 26853531 |
| 2016-04-02 10:46:00 | analysis of FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma | 25608663 |
| 2015-07-25 10:58:00 | this study identified the HUSH (human silencing hub) complex, comprising three poorly characterized proteins, TASOR, MPP8, and periphilin; this complex is absent from Drosophila but is conserved from fish to humans. | 26022416 |
| 2010-07-19 11:08:00 | Data show that periphilin displays an overlapping expression pattern with synphilin-1 in cellular and animal models and in Lewy bodies of Parkinson's disease (PD) patients, and support involvement of periphilin in PD. | 19730898 |
| Type | IDs |
|---|---|
| Synonymous | CR, HSPC206, HSPC232 |
| Gene |
UniProtKB-ID:
PPHLN_HUMAN
UniprotKB:
Q8NEY8
UniParc:
UPI0000351A1E,
UPI0000406AF5,
UPI000023C3D8,
UPI000006E966,
UPI0000D4E933,
UPI000034ECAF,
UPI0000074372,
UPI000006E8D9
EMBL:
AY039238,
AY157850,
AF151066,
AK000186,
BC025306,
CR621833,
AF151040,
AC079684,
BC039832,
AC079601,
AC020629,
AK055690
Ensembl:
ENSG00000134283
KO:
hsa:51535
|
| Nucleutide sequences |
EMBL-CDS:
BAA90996.1,
AAH39832.1,
AAF36152.1,
AAO16497.1,
AAF36126.1,
BAB70985.1,
AAK68657.1,
AAH25306.1
Gene_ORFName:
HSPC232,
HSPC206
Ensembl_TRS:
ENST00000358314,
ENST00000552761,
ENST00000613154,
ENST00000619544,
ENST00000610488,
ENST00000432191,
ENST00000395580,
ENST00000449194,
ENST00000395568
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000449331,
ENSP00000351066,
ENSP00000378947,
ENSP00000393965,
ENSP00000478872,
ENSP00000378935,
ENSP00000477681,
ENSP00000479913,
ENSP00000390681
RefSeq:
NP_001351761.1,
NP_958923.1,
NP_001351758.1,
XP_011536761.1,
XP_016874931.1,
XP_016874938.1,
NP_958846.1,
NP_001137259.1,
NP_001351763.1,
NP_001351753.1,
XP_016874924.1,
XP_016874923.1,
XP_016874934.1,
XP_016874930.1,
NP_057572.5,
NP_001351755.1,
NP_001351752.1,
NP_001351754.1,
NP_958848.1,
NP_001137260.1,
XP_016874928.1,
XP_016874935.1,
XP_016874929.1,
XP_016874939.1,
XP_016874927.1,
XP_016874937.1,
XP_016874933.1,
XP_016874926.1,
NP_001351760.1,
NP_001351756.1,
XP_016874925.1,
NP_001351751.1,
XP_016874932.1,
XP_016874940.1,
NP_001351759.1,
NP_958847.1,
NP_001351762.1,
NP_001137261.1,
NP_001351757.1,
XP_016874936.1
|
| Others |
UniRef100:
UniRef100_Q8NEY8
UniRef90:
UniRef90_Q8NEY8
UniRef50:
UniRef50_Q8NEY8
UniGene:
Hs.444157
CCDS:
CCDS8741.1,
CCDS41773.1,
CCDS44861.1,
CCDS31777.1,
CCDS55817.1,
CCDS44860.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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