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51534 VTA1

51534

VTA1

vesicle trafficking 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition vesicle trafficking 1

研究结论

Date Results Publications
2020-04-04 12:21:00 A structural model of the AQP2-LIP5 complex, giving the very first structural insight into how membrane proteins are recruited to multivesicular bodies inner vesicles. 31661793
2017-09-30 12:04:00 Data suggest that AQP2 binds LIP5 in a AQP2-phosphorylation-dependent manner; phospho-mimicking mutations and phosphorylation reduce thermal stability of AQP2; AQP2 phosphorylation allosterically controls its interaction with LIP5. [AQP2 = aquaporin 2; LIP5 = LYST-interacting protein 5; LYST = lysosomal trafficking regulator protein] 28710278
2015-06-06 14:29:00 Crystal structures of three molecular complexes reveal that IST1 binds to the MIT domains of VPS4 and LIP5. 25657007
2015-05-30 11:27:00 ESCRT-III protein CHMP5 inhibits LIP5-mediated VPS4 activation by inducing a moderate conformational change within LIP5. 25637630
2015-02-07 11:18:00 Vps4 stimulatory element of the cofactor Vta1 contacts the ATPase Vps4 alpha7 and alpha9 subunits to stimulate ATP hydrolysis. 25164817

名称对应

Type IDs
Synonymous C6orf55, DRG-1, DRG1, HSPC228, LIP5, My012, SBP1
Gene
UniProtKB-ID: VTA1_HUMAN, A0A087WY55_HUMAN
UniprotKB: Q9NP79, A0A087WY55
UniParc: UPI0002064FAE, UPI0000034E19, UPI0000E211BB
EMBL: AK301376, BC006989, BC005937, AL136684, AF271994, CR457207, BC022536, KF458307, AF060225, AL033522, AF151062, CH471051, AK000051
Ensembl: ENSG00000009844
KO: hsa:51534
Nucleutide sequences
EMBL-CDS: AAG43125.1, CAG33488.1, BAG62917.1, BAA90909.1, AAF36148.1, AAF76210.1, CAB66619.1, AAH05937.1, EAW47885.1, EAW47883.1, AAH22536.1, AAH06989.1, EAW47884.1
Gene_ORFName: My012, HSPC228, hCG_18120
Ensembl_TRS: ENST00000452973, ENST00000367630, ENST00000620996
Protein sequencees
Ensembl_PRO: ENSP00000356602, ENSP00000395767, ENSP00000481525
RefSeq: NP_057569.2, NP_001273300.1, NP_001273301.1
Others
UniRef100: UniRef100_A0A087WY55, UniRef100_Q9NP79
UniRef90: UniRef90_Q9NP79
UniRef50: UniRef50_Q9NP79
UniGene: Hs.431367
CCDS: CCDS5197.1, CCDS69214.1

全选

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