| Type | Description |
|---|---|
| Definition | anaphase promoting complex subunit 11 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-19 11:32:00 | Overexpression of APC11 is correlated with chromosomal instability in colorectal cancer. An association is observed between APC11 expression and lymphovascular invasion and residual tumor. High levels of APC11 protein in primary colorectal tumors is specifically correlated with metastasis at diagnosis. | 29743633 |
| 2013-01-12 10:02:00 | siRNA targeted against Apc11 could hamper entry into G2/M phase. | 23007976 |
| 2011-01-01 11:34:00 | The authors showed, in vitro, a direct interaction between Orf virus anaphase promoting complex regulator and APC2 and its interference with interactions between APC11 and APC2. | 20826619 |
| 2010-02-08 11:22:00 | Studies indicate that APC/C(Cdh1) is required to maintain genomic stability. | 19826416 |
| 2010-01-21 00:00:00 | APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex. | 11739784 |
| Type | IDs |
|---|---|
| Synonymous | APC11, Apc11p, HSPC214 |
| Gene |
UniProtKB-ID:
APC11_HUMAN,
A0A024R8S1_HUMAN
UniprotKB:
Q9NYG5,
A0A024R8S1
UniParc:
UPI0000001238,
UPI0000374311
EMBL:
BC104641,
BC095454,
BC171899,
BC171900,
BC066308,
AF151048,
AF247789,
AC145207,
BC171892,
BC171898,
AF247565,
BC000607,
CH471099
Ensembl:
ENSG00000141552
KO:
hsa:51529
|
| Nucleutide sequences |
EMBL-CDS:
AAH66308.1,
AAH00607.2,
AAI04642.1,
AAH95454.1,
AAI71900.1,
AAF65816.1,
AAI71892.1,
AAF36134.1,
AAL95694.1,
AAI71899.1,
AAI71898.1,
EAW89703.1,
EAW89700.1
Gene_ORFName:
HSPC214,
hCG_1747917
Ensembl_TRS:
ENST00000572851,
ENST00000392376,
ENST00000572639,
ENST00000579978,
ENST00000578550,
ENST00000574924,
ENST00000344877,
ENST00000357385,
ENST00000575195,
ENST00000571874,
ENST00000571570,
ENST00000577747,
ENST00000571024,
ENST00000583839
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000463567,
ENSP00000460678,
ENSP00000376181,
ENSP00000458143,
ENSP00000463640,
ENSP00000460064,
ENSP00000458515,
ENSP00000458265,
ENSP00000459200,
ENSP00000461648,
ENSP00000339695,
ENSP00000463598,
ENSP00000349957,
ENSP00000464615
RefSeq:
NP_001002249.1,
NP_057560.8,
NP_001002244.1,
NP_001002247.1,
NP_001276343.1,
NP_001002248.1,
NP_001276349.1,
NP_001002245.1,
NP_001002246.1,
NP_001276345.1,
NP_001276344.1,
NP_001276346.1
|
| Others |
UniRef100:
UniRef100_A0A024R8S1,
UniRef100_Q9NYG5
UniRef90:
UniRef90_A0A2I2YY63,
UniRef90_Q9NYG5
UniRef50:
UniRef50_A0A2I2YY63,
UniRef50_Q9NYG5
UniGene:
Hs.534456
CCDS:
CCDS11789.1,
CCDS32769.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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