| Type | Description |
|---|---|
| Definition | phosphodiesterase 9A |
| Date | Results | Publications |
|---|---|---|
| 2015-06-20 11:28:00 | PDE9A can regulate cGMP signalling independent of the nitric oxide pathway, and its role in stress-induced heart disease suggests potential as a therapeutic target. | 25799991 |
| 2013-03-23 10:35:00 | it is concluded that assessment of PDE5 and PDE9 expression may be useful in the differential diagnosis of benign and malignant breast disease and successful treatment of breast cancer | 22960860 |
| 2012-08-25 10:20:00 | In vivo effects of PDE9A inhibition included reversal of the respective disruptions of working memory. | 22328573 |
| 2012-05-05 10:05:00 | PDE9 is widely distributed in the urothelial epithelium of the human lower urinary tract and its potential roles may be different from those of PDE5. | 21736695 |
| 2011-10-15 11:28:00 | Data show that PDE9A inhibitor, BAY-73-6691, significantly reduced basal and sickle cell (SCA) neutrophil adhesion; this was accompanied by decreased SCA neutrophil surface expressions of the L-selectin and CD11b adhesion molecules. | 21336703 |
| Type | IDs |
|---|---|
| Synonymous | HSPDE9A2 |
| Gene |
UniProtKB-ID:
PDE9A_HUMAN,
A0A0S2Z4A3_HUMAN,
A0A0S2Z4T6_HUMAN,
A0A0S2Z475_HUMAN
UniprotKB:
O76083,
A0A0S2Z4A3,
A0A0S2Z4T6,
A0A0S2Z475
UniParc:
UPI000000D8C7,
UPI000000D8CD,
UPI000002A6EA,
UPI0000000C9C,
UPI0000497E01,
UPI000000D8C6,
UPI000000D8C8,
UPI000000D8C9,
UPI000000D8CB,
UPI000000D8CF,
UPI000000D8CC,
UPI000000D8CA,
UPI000002A6EB,
UPI000000D8CE,
UPI0000127C02,
UPI000000D8D0
EMBL:
AF048837,
AY196307,
AF067226,
KU178247,
AY196304,
AY196310,
AP001747,
AY196313,
BT007016,
AY196306,
KU178248,
AF067225,
AY242121,
AB017602,
AY196305,
KU178246,
AF067224,
BC009047,
AY196309,
AK294112,
AY196302,
AY196314,
AY196300,
AY196312,
AY196299,
AK314679,
AY196311,
AY701187,
AY196308,
CH471079,
AF067223,
AY196301,
AY196303
Ensembl:
ENSG00000160191
KO:
hsa:5152
|
| Nucleutide sequences |
EMBL-CDS:
EAX09540.1,
AAO34691.1,
AAO34700.1,
AAO34689.1,
AAO34694.1,
AAH09047.1,
AAO34693.1,
BAG37232.1,
AAC26726.1,
AAO34696.1,
AAO34698.1,
AAO34685.1,
BAA95552.1,
EAX09542.1,
EAX09546.1,
AAO34688.1,
AAP35662.1,
AAO34687.1,
EAX09541.1,
AAO34695.1,
AAO34690.1,
AAO34692.1,
AAC26725.1,
AAC26724.1,
EAX09536.1,
EAX09549.1,
BAG57446.1,
BAA88847.1,
AAO34697.1,
EAX09537.1,
AAC26723.1,
EAX09548.1,
EAX09544.1,
AAO88210.1,
AAV84271.1,
AAO34699.1,
AAO34686.1,
AAC39778.1,
ALQ33704.1,
ALQ33705.1,
ALQ33706.1,
EAX09532.1
Gene_ORFName:
hCG_401272
Ensembl_TRS:
ENST00000335512,
ENST00000291539,
ENST00000398227,
ENST00000398234,
ENST00000398229,
ENST00000398236,
ENST00000349112,
ENST00000398232,
ENST00000380328,
ENST00000398225,
ENST00000328862,
ENST00000335440,
ENST00000398224
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000381281,
ENSP00000335365,
ENSP00000328699,
ENSP00000381287,
ENSP00000381289,
ENSP00000381280,
ENSP00000335242,
ENSP00000344730,
ENSP00000381291,
ENSP00000291539,
ENSP00000381283,
ENSP00000369685,
ENSP00000381285
RefSeq:
NP_001001567.1,
NP_001001582.1,
NP_001001571.1,
NP_001001572.1,
NP_001001585.1,
NP_001302462.1,
NP_001001568.1,
XP_011527902.1,
NP_001001579.1,
NP_001001575.1,
XP_016883855.1,
NP_001001578.1,
NP_001001574.1,
NP_001001570.1,
NP_001001580.1,
NP_001001569.1,
XP_016883856.1,
NP_002597.1,
XP_011527900.1,
NP_001001581.1,
NP_001001583.1,
NP_001001576.1,
XP_024307852.1,
NP_001001573.1,
NP_001001577.1,
NP_001001584.1
|
| Others |
UniRef100:
UniRef100_O76083-2,
UniRef100_O76083-4,
UniRef100_O76083
UniRef90:
UniRef90_O76083,
UniRef90_O76083-4
UniRef50:
UniRef50_O76083-4,
UniRef50_O76083
UniGene:
Hs.473927
CCDS:
CCDS33568.1,
CCDS42945.1,
CCDS42943.1,
CCDS42942.1,
CCDS33567.1,
CCDS33570.1,
CCDS42944.1,
CCDS33569.1,
CCDS13690.1,
CCDS42946.1,
CCDS42941.1,
CCDS33571.1,
CCDS42947.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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