| Type | Description |
|---|---|
| Definition | NCK interacting protein with SH3 domain |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 11:49:00 | The findings suggest that SPIN90, as an adaptor protein, simultaneously binds inactive Rab5 and Gapex5, thereby altering their spatial proximity and facilitating Rab5 activation. | 31358736 |
| 2019-10-05 11:14:00 | Structure of the nucleation-promoting factor SPIN90 bound to the actin filament nucleator Arp2/3 complex. | 30322896 |
| 2017-11-04 12:40:00 | Low SPIN90 expression is associated with Breast Cancer. | 28652253 |
| 2014-09-20 10:59:00 | findings suggest that SPIN90 contributes to the formation and movement of endosomal vesicles, and modulates the stability of EGFR protein, which affects cell cycle progression | 24340049 |
| 2013-12-21 10:35:00 | SPIN90 dephosphorylation is a prerequisite step for releasing cofilin so that cofilin can adequately sever actin filaments into monomeric form. | 23765104 |
| Type | IDs |
|---|---|
| Synonymous | AF3P21, DIP, DIP1, ORF1, SPIN90, VIP54, WASLBP, WISH |
| Gene |
UniProtKB-ID:
SPN90_HUMAN
UniprotKB:
Q9NZQ3
UniParc:
UPI0000231B5D,
UPI0000000DFA,
UPI0000135D86,
UPI000002B40F,
UPI0001D89702
EMBL:
BC016052,
AJ242655,
AB069982,
AF178432,
AK294151,
BC026280,
AC141002,
AB069981,
AF303581,
AY453794
Ensembl:
ENSG00000213672
KO:
hsa:51517
|
| Nucleutide sequences |
EMBL-CDS:
AAH26280.1,
AAH16052.1,
AAR83735.1,
BAB63204.1,
BAB63205.1,
AAK09094.1,
CAB65089.2,
BAG57476.1,
AAF35985.1
Ensembl_TRS:
ENST00000416649,
ENST00000294129
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000294129,
ENSP00000389059
RefSeq:
XP_016862088.1,
XP_016862083.1,
XP_016862086.1,
XP_016862084.1,
XP_016862089.1,
XP_016862085.1,
NP_057537.1,
NP_909119.1,
XP_016862087.1
|
| Others |
UniRef100:
UniRef100_Q9NZQ3
UniRef90:
UniRef90_Q9NZQ3
UniRef50:
UniRef50_Q9NZQ3
UniGene:
Hs.655006
CCDS:
CCDS2776.1,
CCDS46827.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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