| Type | Description |
|---|---|
| Definition | G2 and S-phase expressed 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-13 15:35:00 | GTSE1, together with CDC20, PCNA, and MCM6, may synergistically promote adverse prognosis in hepatocellular carcinoma by activating cell cycle. | 32082966 |
| 2019-08-24 10:59:00 | Authors found that GTSE1 could regulate the p53 function to alter the cell cycle distribution dependent on the mutation state of p53. Results reveal that GTSE1 played a key role in the progression of breast cancer. | 30961661 |
| 2019-04-20 12:16:00 | Knockdown of GTSE1 obviously suppressed the proliferation, migration, and invasion capacity whereas increasing GTSE1 led to the opposite trend, which suggested that GTSE1 could serve as a potential therapeutic target for bladder cancer. GTSE1 overexpression in bladder cancer might participate in the regulation of FoxM1/CCNB1 expression via the induction of the transfer of p53 to cytoplasm | 30414902 |
| 2019-01-19 10:48:00 | High expression of GTSE1 is commonly noted in hepatocellular carcinoma (HCC) and is closely correlated with migration and invasion by epithelial-to-mesenchymal transition modulation. Activated GTSE1 significantly interferes with chemotherapy efficacy and influences the probability of survival of patients with HCC. | 28698581 |
| 2018-06-23 10:48:00 | G2 and S-phase expressed 1 (GTSE1) expression promotes AM progression and correlates with clinical outcomes of patients with acral melanoma (AM), and may represent a promising therapeutic target to suppress AM progression. | 29660787 |
| Type | IDs |
|---|---|
| Synonymous | B99 |
| Gene |
UniProtKB-ID:
GTSE1_HUMAN
UniprotKB:
Q9NYZ3
UniParc:
UPI000013C5A1
EMBL:
BC006325,
Z93024,
AK315550,
AK222806,
BC075828,
AF223408,
AL031588,
CT841519
Ensembl:
ENSG00000075218
KO:
hsa:51512
|
| Nucleutide sequences |
EMBL-CDS:
CAJ86449.1,
AAH06325.1,
AAH75828.1,
BAD96526.1,
AAF31459.1,
BAG37928.1
Ensembl_TRS:
ENST00000454366
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000415430
RefSeq:
XP_016884305.1,
XP_011528515.1,
NP_057510.5,
XP_005261684.1
|
| Others |
UniRef100:
UniRef100_Q9NYZ3
UniRef90:
UniRef90_Q9NYZ3
UniRef50:
UniRef50_Q9NYZ3
UniGene:
Hs.386189,
Hs.439524
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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