| Type | Description |
|---|---|
| Definition | charged multivesicular body protein 5 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-23 12:59:00 | Our findings show that CHMP5 is a direct target of MIR429 in human colon cancer cell lines and suggest that CHMP5 up-regulation as a result of reduced MIR429 expression in DSS-induced mice colitis tissues and human UC tissues may restrict apoptosis and promote cell proliferation. | 30334065 |
| 2016-10-22 11:02:00 | CHMP5 might be involved in the homeostatic regulation of TCR on the cell surface, presumably through TCR recycling or degradation. Thus CHMP5 is implicated in TCR-mediated signaling. | 26821576 |
| 2015-05-30 11:27:00 | ESCRT-III protein CHMP5 inhibits LIP5-mediated VPS4 activation by inducing a moderate conformational change within LIP5. | 25637630 |
| 2013-11-02 11:36:00 | after CHMP5 inhibition, both Granzyme B/Perforin apoptotic pathway and apoptosis-inducing factor-mediated necrotic pathway were activated, while autophagic pathway was not activated | 23619569 |
| 2010-09-15 22:05:00 | was shown to be anti-apoptotic and may participate in leukemogenesis | 17855796 |
| Type | IDs |
|---|---|
| Synonymous | C9orf83, CGI-34, HSPC177, PNAS-2, SNF7DC2, Vps60 |
| Gene |
UniProtKB-ID:
CHMP5_HUMAN
UniprotKB:
Q9NZZ3
UniParc:
UPI000021126C,
UPI000003602D
EMBL:
BC020796,
AF132968,
AK295744,
AF275810,
AF229832,
BC006974,
BC007457,
AL356472,
AK315455,
AF161525,
BC016698,
CH471071,
BC021168
Ensembl:
ENSG00000086065
KO:
hsa:51510
|
| Nucleutide sequences |
EMBL-CDS:
BAG58578.1,
AAF29140.1,
AAH16698.1,
AAH21168.1,
AAF42917.1,
EAW58512.1,
AAH06974.1,
AAH07457.1,
BAG37842.1,
AAG23821.1,
AAH20796.1,
AAD27743.1
Gene_ORFName:
PNAS-114,
CGI-34,
PNAS-2,
HSPC177
Ensembl_TRS:
ENST00000223500,
ENST00000419016
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000442725,
ENSP00000223500
RefSeq:
NP_001182465.1,
NP_057494.3
|
| Others |
UniRef100:
UniRef100_Q9NZZ3
UniRef90:
UniRef90_Q9NZZ3
UniRef50:
UniRef50_Q9NZZ3
UniGene:
Hs.635313
CCDS:
CCDS6537.1,
CCDS56569.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员