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51504 TRMT112

51504

TRMT112

tRNA methyltransferase subunit 11-2

protein-coding

Homo sapiens

基因描述

Type Description
Definition tRNA methyltransferase subunit 11-2

研究结论

Date Results Publications
2021-02-27 13:47:00 Structural insight into HEMK2-TRMT112-mediated glutamine methylation. 32969463
2020-07-11 12:39:00 The down-regulation of TRMT112 does not affect the N6AMT1 protein levels in cells, suggesting that the two proteins of TRMT112 network, WBSCR22 and N6AMT1, are differently regulated by their common cofactor. 31466382
2019-12-07 10:48:00 METTL5-TRMT112 partners act by extruding the adenosine to be modified from a double-stranded nucleic acid. 31328227
2016-05-07 11:25:00 The localization of the TRMT112 protein is determined by WBSCR22, and the WBSCR22-TRMT112 complex is localized in the cell nucleus. 26214185
2016-03-12 11:11:00 DIMT1L and WBSCR22-TRMT112 are required for distinct pre-rRNA processing reactions leading to synthesis of 18S rRNA. Ribosome biogenesis requires the presence of the modification enzyme rather than its RNA-modifying catalytic activity. 25851604

名称对应

Type IDs
Synonymous HSPC152, HSPC170, TRM112, TRMT11-2, hTrm112
Gene
UniProtKB-ID: TR112_HUMAN, A0A024R565_HUMAN, F5GX77_HUMAN
UniprotKB: Q9UI30, A0A024R565, F5GX77
UniParc: UPI0000405A18, UPI00000473D9, UPI000204AEAF
EMBL: BC017172, CH471076, AP001453, AK312050, AF229068, BC105294, AF110774, BC029482, AF161501, KF455402
Ensembl: ENSG00000173113
KO: hsa:51504
Nucleutide sequences
EMBL-CDS: AAH29482.1, AAI05295.1, BAG34986.1, AAH17172.1, AAF82266.1, EAW74251.1, AAF29116.1, AAF14857.1, EAW74252.1
Gene_ORFName: AD-001, HSPC152, HSPC170, hCG_23383
Ensembl_TRS: ENST00000544844, ENST00000308774, ENST00000539854
Protein sequencees
Ensembl_PRO: ENSP00000309433, ENSP00000438349, ENSP00000440437
RefSeq: NP_001273013.1, NP_001359000.1, NP_057488.1, NP_001273011.1, NP_001359001.1
Others
UniRef100: UniRef100_F5GX77, UniRef100_Q9UI30
UniRef90: UniRef90_Q9UI30, UniRef90_F5GX77
UniRef50: UniRef50_Q9UI30, UniRef50_G1DGA8
UniGene: Hs.333579
CCDS: CCDS8068.1, CCDS66113.1

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