| Type | Description |
|---|---|
| Definition | phosphodiesterase 7A |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:23:00 | Phosphodiesterase 7 Regulation in Cellular and Rodent Models of Parkinson's Disease. | 31473904 |
| 2018-06-16 10:49:00 | Here we describe a compound, BC54, that is a selective inhibitor of enzymes from the cAMP-specific PDE4 and PDE7 families. Consistent with the biological effect of other PDE4 and PDE7 inhibitors, BC54 displays potent anti-inflammatory properties and is superior to a combination of rolipram (a PDE4 inhibitor) and BRL50481 (a PDE7A inhibitor) for inducing apoptosis in chronic lymphocytic leukemia (CLL) cells | 28867658 |
| 2017-09-16 12:45:00 | Low PDE7A expression is associated with sepsis. | 28356347 |
| 2014-11-22 12:34:00 | PDE7A is a high-speed and low-affinity phosphodiesterase for cCMP. | 25128584 |
| 2013-11-16 11:52:00 | PDE7 has roles in regulating oligodendrocyte precursor survival and differentiation during brain development and in adulthood | 23661015 |
| Type | IDs |
|---|---|
| Synonymous | HCP1, PDE7 |
| Gene |
UniProtKB-ID:
PDE7A_HUMAN
UniprotKB:
Q13946
UniParc:
UPI000004E8B3,
UPI0000127BFD,
UPI000002A6E5
EMBL:
L12052,
U67932,
AC055822,
BC126360,
AC100812,
AK292680,
AK290801,
AF332652
Ensembl:
ENSG00000205268
KO:
hsa:5150
|
| Nucleutide sequences |
EMBL-CDS:
AAA35644.2,
AAB65772.1,
BAF85369.1,
AAK57640.1,
AAI26361.1,
BAF83490.1
Ensembl_TRS:
ENST00000401827,
ENST00000396642,
ENST00000379419
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000368730,
ENSP00000385632,
ENSP00000379881
RefSeq:
NP_001229247.1,
XP_016869027.1,
XP_011515842.1,
NP_002594.1
|
| Others |
UniRef100:
UniRef100_Q13946
UniRef90:
UniRef90_Q13946
UniRef50:
UniRef50_Q13946
UniGene:
Hs.527119
CCDS:
CCDS34901.1,
CCDS56538.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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