| Type | Description |
|---|---|
| Definition | TP53 regulated inhibitor of apoptosis 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:16:00 | TRIAP1 knockdown sensitizes non-small cell lung cancer to ionizing radiation by disrupting redox homeostasis. | 32096592 |
| 2019-10-05 12:49:00 | miR-1301 was implicated in the chemosensitivity of osteosarcoma to epirubicin by modulating TRIAP1. | 31433581 |
| 2019-05-11 13:16:00 | Inhibition of TRIAP1 in RPMI8226 cells increased the percentage of apoptotic cells, accompanied by increased expression of APAF1 and Caspase 9, and Caspase 9 and Caspase 3/7 activity. | 27032384 |
| 2017-04-01 12:41:00 | TRIAP1 is regulated by miR-320b and has a role in progression in nasopharyngeal carcinoma | 27428374 |
| 2016-04-23 11:40:00 | crystal structures of free TRIAP1 and TRIAP1-SLMO1 complex reveal how the PRELI domain is chaperoned during import into the intermembrane mitochondrial space; structural resemblance of PRELI-like domain of SLMO1 with that of mammalian phoshatidylinositol transfer proteins suggest they share similar lipid transfer mechanisms | 26071602 |
| Type | IDs |
|---|---|
| Synonymous | HSPC132, MDM35, P53CSV, WF-1 |
| Gene |
UniProtKB-ID:
TRIA1_HUMAN
UniprotKB:
O43715
UniParc:
UPI0000124E0B
EMBL:
U75688,
AF161481,
AL021546,
CH471054,
BC002638,
BC055313,
AK312006
Ensembl:
ENSG00000170855
KO:
hsa:51499
|
| Nucleutide sequences |
EMBL-CDS:
AAH55313.1,
AAH02638.1,
AAF29096.1,
EAW98192.1,
BAG34944.1,
AAR00584.1
Gene_ORFName:
HSPC132
Ensembl_TRS:
ENST00000546954
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000449795
RefSeq:
NP_057483.1
|
| Others |
UniRef100:
UniRef100_O43715
UniRef90:
UniRef90_O43715
UniRef50:
UniRef50_O43715
UniGene:
Hs.69499
CCDS:
CCDS9198.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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